Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review

E Maloney-Wilensky, V Gracias, A Itkin… - Critical care …, 2009 - journals.lww.com
Objective: In this study, available medical literature were reviewed to determine whether
brain hypoxia as measured by brain tissue oxygen (Bto 2) levels is associated with …

[HTML][HTML] Effects of brain tissue oxygen (PbtO2) guided management on patient outcomes following severe traumatic brain injury: a systematic review and meta …

LMC Hays, A Udy, AA Adamides, JR Anstey… - Journal of clinical …, 2022 - Elsevier
Monitoring and optimisation of brain tissue oxygen tension (PbtO 2) has been associated
with improved neurological outcome and survival in observational studies of severe …

Medical management of compromised brain oxygen in patients with severe traumatic brain injury

LE Bohman, GG Heuer, L Macyszyn… - Neurocritical care, 2011 - Springer
Abstract Background Brain tissue oxygen (PbtO 2) monitoring is used in severe traumatic
brain injury (TBI) patients. How brain reduced PbtO 2 should be treated and its response to …

Brain tissue oxygen monitoring and hyperoxic treatment in patients with traumatic brain injury

C Beynon, KL Kiening, B Orakcioglu… - Journal of …, 2012 - liebertpub.com
Cerebral ischemia is a well-recognized contributor to high morbidity and mortality after
traumatic brain injury (TBI). Standard of care treatment aims to maintain a sufficient oxygen …

Physiologic and functional outcome correlates of brain tissue hypoxia in traumatic brain injury

JJJ Chang, TS Youn, D Benson, H Mattick… - Critical care …, 2009 - journals.lww.com
Objective: Assess the prevalence of brain tissue hypoxia in patients with severe traumatic
brain injuries (TBI), and to characterize the relationship between brain tissue hypoxia and …

Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury

G Rosenthal, JC Hemphill III, M Sorani… - Critical care …, 2008 - journals.lww.com
Objectives: Despite the growing clinical use of brain tissue oxygen monitoring, the specific
determinants of low brain tissue oxygen tension (P bt o 2) following severe traumatic brain …

Brain tissue oxygen–directed management and outcome in patients with severe traumatic brain injury

AM Spiotta, MF Stiefel, VH Gracias, AM Garuffe… - Journal of …, 2010 - thejns.org
Object The object of this study was to determine whether brain tissue oxygen (PbtO 2)–
based therapy or intracranial pressure (ICP)/cerebral perfusion pressure (CPP)–based …

Focal cerebral oxygenation and neurological outcome with or without brain tissue oxygen-guided therapy in patients with traumatic brain injury

AA Adamides, DJ Cooper, FL Rosenfeldt, MJ Bailey… - Acta …, 2009 - Springer
Background In patients with severe traumatic brain injury (TBI), the depth and duration of
cerebral hypoxia are independent predictors of outcome. This study aimed to evaluate the …

Brain oxygen optimization in severe traumatic brain injury phase-II: a phase II randomized trial

DO Okonkwo, LA Shutter, C Moore… - Critical care …, 2017 - journals.lww.com
Objectives: A relationship between reduced brain tissue oxygenation and poor outcome
following severe traumatic brain injury has been reported in observational studies. We …

Brain tissue oxygen monitoring in traumatic brain injury and major trauma: outcome analysis of a brain tissue oxygen–directed therapy

PK Narotam, JF Morrison, N Nathoo - Journal of neurosurgery, 2009 - thejns.org
Object Cerebral ischemia is the leading cause of preventable death in cases of major
trauma with severe traumatic brain injury (TBI). Intracranial pressure (ICP) control and …