During the progression of the neurodegenerative process, mitochondria participates in
several intercellular signaling pathways. Voltage-dependent anion-selective channel 1 …

Voltage-Dependent Anion Channel 1 (VDAC1) is a mitochondrial outer membrane protein
that plays a crucial role in regulating cellular energy metabolism and apoptosis by mediating …

Background Alzheimer's disease (AD) exhibits mitochondrial dysfunctions associated with
dysregulated metabolism, brain inflammation, synaptic loss, and neuronal cell death. As a …

Impaired mitochondrial function has been proposed as a causative factor in
neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), caused by motor …

The multifunctional protein, voltage-dependent anion channel 1 (VDAC1), is located on the
mitochondrial outer membrane. It is a pivotal protein that maintains mitochondrial function to …

Beta‐amyloid (Aβ) accumulation in the brains of Alzheimer's disease (AD) patients leads to
mitochondrial dysfunction and ferroptosis in neurons. Voltage‐dependent anion channel 1 …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder. Although an
accumulation of brain amyloid-β (Aβ) peptide and hyperphosphorylated tau protein have …

The voltage-dependent anion channel 1 (VDAC1) was first described as a mitochondrial
porin that mediates the flux of metabolites and ions, thereby integrating both cell survival …

Mitochondria are the key source of ATP that fuels cellular functions, and they are also central
in cellular signaling, cell division and apoptosis. Dysfunction of mitochondria has been …

Mitochondrial dysfunction has been implicated in the pathogenesis of Alzheimer's disease, a
neurodegenerative disorder characterized by progressive cognitive decline. Voltage …