Acetaminophen (APAP) overdose-induced hepatotoxicity is the most common cause of drug-
induced liver injury worldwide, which is significantly linked to oxidative stress and sterile …

To explore the action time and molecular mechanism underlying the effect of
acetaminophen (APAP) on liver injury. APAP was used to establish drug-induced liver injury …

Rosmarinic acid (RA) is a natural polyphenol with various biological activities, such as anti-
oxidative, anti-fibrotic, and hepatoprotective properties. The objective of this study was to …

Acetaminophen (APAP)-induced liver injury is a common hepatic disease resulting from
drug abuse. Few targeted treatments are available clinically nowadays. The flower bud of …

Acetaminophen (APAP) overdose is a major cause of drug-induced liver injury worldwide.
Our current study was performed to assess the potential protective effects of γ-oryzanol …

Farrerol has been shown to have antioxidative potential via Nrf2 activation, which in turn is
involved in the prevention of hepatotoxicity. The purpose of the current study was to explore …

Acetaminophen (APAP) is used drugs worldwide for treating pain and fever. However, APAP
overdose is the principal cause of acute liver failure in Western countries. Salvianolic acid B …

Acetaminophen (APAP) overdose-induced acute liver damage is mostly due to
overwhelmingly increased oxidative stress. Nuclear factor-erythroid 2-related factor2 (Nrf2) …

Background Acetaminophen (APAP) overdose-induced acute liver failure (ALF) is mainly
resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) …

Acetaminophen (APAP) overdose-induced fatal hepatotoxicity is majorly characterized by
overwhelmingly increased oxidative stress while enhanced nuclear factor-erythroid 2 …