Alternative splicing of the RBP1 gene clusters in an internal exon that encodes potential phosphorylation sites.
GA Otterson, RA Kratzke, AY Lin, PG Johnston… - Oncogene, 1993 - europepmc.org
We have isolated cDNA and genomic clones for the human retinoblastoma binding protein 1
(RBP1) gene, and have identified alternative splicing of RBP1 clustered within a 207 …
(RBP1) gene, and have identified alternative splicing of RBP1 clustered within a 207 …
A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding.
FJ Kaye, RA Kratzke, JL Gerster… - Proceedings of the …, 1990 - National Acad Sciences
We have previously identified a small-cell lung cancer cell line (NCI-H209) that expresses
an aberrant, underphosphorylated form of the retinoblastoma protein RB1. Molecular …
an aberrant, underphosphorylated form of the retinoblastoma protein RB1. Molecular …
Characterization of the retinoblastoma binding proteins RBP1 and RBP2.
The retinoblastoma gene product, pRB, regulates cell proliferation by binding to and
inhibiting the activity of key growth promoting proteins. Several cellular proteins have been …
inhibiting the activity of key growth promoting proteins. Several cellular proteins have been …
cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene product
Y Sakai, M Saijo, K Coelho, T Kishino, N Niikawa… - Genomics, 1995 - Elsevier
We have previously isolated cDNA of a novel protein (RBQ-1, HGMW-approved symbol
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …
Enhanced tumor cell growth suppression by an N-terminal truncated retinoblastoma protein.
HJ Xu, K Xu, Y Zhou, J Li… - Proceedings of the …, 1994 - National Acad Sciences
The retinoblastoma (RB) gene encodes a nuclear phosphoprotein of 928 amino acids
(pRB). Thus far, much effort in RB research has been focused on both the viral oncoprotein …
(pRB). Thus far, much effort in RB research has been focused on both the viral oncoprotein …
Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product
D Defeo-Jones, PS Huang, RE Jones, KM Haskell… - Nature, 1991 - nature.com
THE E7 transforming protein of human papilloma virus-16 binds to the retinoblastoma gene
product (pRb) 1, 2 through a nine-amino-acid segment of E7 (21–29) 3–5. This segment of …
product (pRb) 1, 2 through a nine-amino-acid segment of E7 (21–29) 3–5. This segment of …
Cloning and sequence of the rat retinoblastoma (Rb) gene cDNA.
NK Roy, A Ballesteros, SJ Garte - Nucleic acids research, 1993 - ncbi.nlm.nih.gov
The retinoblastoma (RB) susceptibility gene serves as a model for the study of tumor
suppressor genes. The human and mouse RB genes have been thoroughly characterized …
suppressor genes. The human and mouse RB genes have been thoroughly characterized …
DNA-binding activity of retinoblastoma protein is intrinsic to its carboxyl-terminal region.
The retinoblastoma (RB) gene encodes a nuclear phosphoprotein with a molecular weight
of 110,000 (pp110RB) associated with DNA-binding activity. This sequence-nonspecific …
of 110,000 (pp110RB) associated with DNA-binding activity. This sequence-nonspecific …
Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping
M Saijo, Y Sakai, T Kishino, N Niikawa, Y Matsuura… - Genomics, 1995 - Elsevier
We have isolated distinct clones for cellular proteins that bind to the retinoblastoma protein
by direct screening of cDNA expression libraries using purified pRB as a probe. The total …
by direct screening of cDNA expression libraries using purified pRB as a probe. The total …
C-terminal truncation of the retinoblastoma gene product leads to functional inactivation.
JY Shew, BT Lin, PL Chen, BY Tseng… - Proceedings of the …, 1990 - National Acad Sciences
Mutational inactivation of the retinoblastoma (RB) gene has been implicated in the genesis
of retinoblastoma, osteosarcoma, and other human tumors. Our strategy has been to …
of retinoblastoma, osteosarcoma, and other human tumors. Our strategy has been to …