This review examines the biological physics of intracellular transport probed by the coherent
optics of dynamic light scattering from optically thick living tissues. Cells and their …

Intracellular dynamics in living tissue are dominated by active transport driven by
bioenergetic processes far from thermal equilibrium. Intracellular constituents typically …

Dynamic light scattering from three-dimensional intracellular motions in living tissues or
biopsies creates dynamic speckle due to broadband Doppler shifts that are recorded as …

Coherent light scattered by tissues brings structural and dynamic information, at depth, that
standard imaging techniques cannot reach. Dynamics of cells or sub-cellular elements can …

Dynamic speckle from 3-D coherence-gated optical sections provides a sensitive label-free
measure of cellular activity up to 1 mm deep in living tissue. However, specificity to cellular …

Effects that accompany the propagation of laser radiation in tissues and interaction of laser
radiation with cell flows are considered. These effects include diffraction, formation of …

Tissue dynamics spectroscopy uses digital holography as a coherence gate to extract depth-
resolved quasi-elastic dynamic light scattering from inside multicellular tumor spheroids. The …

Optical contrast based on elastic scattering interactions between light and matter can be
used to probe cellular structure, cellular dynamics, and image tissue architecture. The …

Dynamic multiple light scattering (DMLS) has found numerous applications, including soft
matter physics and biomedical optics. Yet biological tissues may have complex internal …

All substances exhibit constant random motion at the microscopic scale. This is a direct
consequence of thermal agitation, and leads to diffusion of molecules and small particles in …