Poor aqueous solubility is a serious problem for most chemotherapeutics. Docetaxel (DTX),
an inhibitor of microtubule depolymerization, is frequently used to treat many malignancies …

The aim of the present study was to prepare, characterize, and evaluate solid lipid
nanoparticles (SLNs) containing docetaxel (DTX) to improve the efficacy of this …

Docetaxel, an inhibitor of microtubule depolymerization, has been used for many
malignancies. Due to its toxicity and the non-selective distribution of its commercial …

Purpose: To further enhance the antitumor efficacy through targeted delivery, DTX loaded
lipid-based-nanosuspensions (DTX-LNS) were prepared and functionalized by PEGylation …

The purpose of the study was to design lipid-based-nanosuspensions (LNS) for Docetaxel
(DTX) without Tween 80 for clinical intravenous administration (iv). DTX-LNS were prepared …

Docetaxel was used extensively in ovarian cancer treatment in the combination with
platinum compound. However, the serious side effect of clinically available formulation limits …

Abstract Objectives Lipid emulsified nanoparticles (LPNPs) have been developed to load
anticancer drug docetaxel (DTX) in this work. Methods We evaluated DTX-loaded lipid …

A well characterized Nanosomal Docetaxel Lipid Suspension (NDLS) formulation was
developed without using any detergent or toxic organic solvents to avoid hypersensitivity …

The usefulness of Docetaxel (DT) as an anti-cancer agent is limited to parenteral route
owing to its very poor oral bioavailability. Thus, to improve its oral efficacy, DT was loaded in …

Docetaxel is an adjuvant chemotherapy drug widely used to treat multiple solid tumors;
however, its toxicity and side effects limit its clinical efficacy. Herein, docetaxel-loaded solid …