Since pregnant and lactating women have historically been excluded from drug
development trials, safety studies need to be conducted postapproval. This study evaluated …

Objective: To provide guidance for clinicians on risk assessment of medication use during
pregnancy and lactation. Data Sources: Authors completed PubMed searches to identify …

Although most drugs are used to treat chronic or pregnancy-induced conditions during
pregnancy and lactation, very few are studied in pregnant or breastfeeding women. The …

In February 2015, given high rates of use of medications by pregnant women and the
relative lack of data on safety and efficacy of many drugs utilized in pregnancy, the Eunice …

Purpose To examine the extent, nature and determinants of medication use in early
pregnancy. Methods We reviewed early pregnancy medication use, as reported to a midwife …

Purpose The present study describes the safety profile of medications used during
pregnancy across European countries and examines maternal factors associated with the …

Globally, more than 200 million women become pregnant each year, most of whom receive
medications despite limited information on their safe use during pregnancy. The paucity of …

Pregnant and breastfeeding women have been rendered therapeutic orphans as they have
been historically excluded from clinical trials. Labelling for most approved drugs does not …

Almost 100% of pregnant women are exposed to medications during pregnancy [1]. While
thousands of pregnant and breastfeeding women ingest either a prescribed or over …

Relatively few drugs, especially those recently approved by the US Food and Drug
Administration, have published human pregnancy experience. Although all drugs contain …