Capsaicin, the active ingredient in hot chilli peppers, has selective actions on unmyelinated
C-fibres and thinly myelinated A primary sensory neurones [37, 100](Table 1). Most …

Abstract The effect of Ruthenium Red on the antinociceptive action of capsaicinoids was
investigated using tail-flick test in mice. Capsaicin and KR-25018, when administered …

Capsaicin, the active ingredient in hot peppers, produces a long-lasting reduction of
nociceptive reactions in rodents through a selective toxic action on afferent C-fibres …

Capsaicin pharmacology. Capsaicin is a chemical derivative of vanillyl amide, 8-methyl-N-
vanillyl-6-nonenamide and has a molecular weight of 305.42. Hot peppers have been eaten …

1 The motor effects of capsaicin on the guinea‐pig distal colon have been investigated in
vivo and in vitro. 2 Capsaicin (0.1–10 μg kg− 1 iv) produced a transient relaxation which was …

In the late fifties and sixties Jancso published a series of papers on 'the peculiar
pharmacological effect of capsaicin Capsaicin or 8-methyl-N-vanillyi-6-nonenamide is the …

Rats were treated with 50 mg/kg capsaicin on the second day of life or at the age of 2–3
months. The effect of morphine on the nociceptive threshold, as determined by the reaction …

Both systemic and intrathecal capsaicin release and deplete substance P from primary
sensory afferents and induce prolonged chemical and thermal analgesia. Given the …

Intrathecal injections of capsaicin (CAP) and 4 other homovanillic acid (HMV) derivatives
related to the structure of CAP were carried out. Capsaicin, 1-nonenoylvanillylamide (NVA) …

The antinociceptive effects of a novel capsaicin analogue, civamide (cis-8-methyl-N-vanillyl-
6-nonenamide), given orally to adult rats were examined. In the formalin test, civamide …