Intrathecal injections of capsaicin (CAP) and 4 other homovanillic acid (HMV) derivatives
related to the structure of CAP were carried out. Capsaicin, 1-nonenoylvanillylamide (NVA) …

1 We have tested the hypothesis that capsaicin‐induced activation, desensitization and
impairment of peripheral nociceptor function is mediated by separate mechanisms. This was …

A series of compounds incorporating replacements for theamide bond “B-region” moiety of
capsaicin have been synthesized, including vanillylamides and esters, homovanillic acid …

After neonatal treatment of rats with capsaicin, the spinal cord, the spinal trigeminal nucleus
and spinal and trigeminal ganglia were analysed with immunohistochemistry using antisera …

Application of capsaicin to the sciatic nerve reduces responsiveness to pain in the foot-flick
test which examines bried, threshold-level pain. The purpose of the present study was to …

The effect of systemic administration of Ruthenium Red on the excitatory and desensitizing
effect of capsaicin was investigated in rats. Ruthenium Red was injected sc 30 min before …

In an attempt to provide more direct evidence concerning the possible antinociceptive effect
of resveratrol-benfotiamine combination on neurogenic pain, we investigated whether …

A series of capsaicin analogues have been synthesized in an attempt to try to separate the
antinociceptive properties of capsaicin from its hypothermic effects. In capsaicin analogues …

The antinociceptive effect of capsaicin to noxious chemical stimuli has been invariably
verified. As to thermal or mechanical nociception, however, routine pharmacological …

As a topical agent, capsaicin reportedly blocks pain without otherwise impairing sensation.
Ten subjects underwent blinded, multiple-dose application of topical 0.025% capsaicin or …