The dental phenolic medicaments, eugenol and guaiacol, are partly similar in chemical
structure to capsaicin, the pungent constituent of chili peppers, which selectively activates …

When applied to peripheral fibres in a neonatal rat tail/spinal cord preparation in vitro,
capsaicin (0.2–50 μM) induced an activation, selective desensitization and reduced …

1 The potassium current in embryo spinal neurones of Xenopus consists of at least two
kinetically distinct components with overlapping voltage‐dependencies of activation. We …

Capsaicin is a principle constituent in a large variety of red peppers (eg, Capsicum annuum,
Capsicum frutescens), and it is to this and closely related substances that the pungency of …

A series of analogues of capsaicin, the pungentprinciple of chilli peppers, was synthesized
and tested in assays for capsaicin-like agonism in vitro. The results of these assays were …

Results Intravenous administration of capsaicin. Capsaicin levels in tissues 3 and 10 min
after iv injection of 2 mg kg-1 are shown in Table 1. Three minutes after iv administration an …

The interaction of capsaicin with microsomal drug-metabolizing systems was assessed to
determine the role that bioactivation of capsaicin may play in the induction of hepatotoxicity …

Vanilloid receptors are activated by capsaicin, the pungent ingredient in hot pepper. They
are also specifically and competitively inhibited by capsazepine (CPZ). To determine …

Over the past several decades capsaicin, a natural product of certain species of red pepper,
has been found to have a broad range of physiological effects in adult animals. Recent …