Background Inflammation is a major cause of temporomandibular disorder‐related pain. The
N av1. 7 sodium channel has a critical function in pain perceptions. However, whether and …

Background The proinflammatory cytokine interleukin-1β (IL-1β) drives pain by inducing the
expression of inflammatory mediators; however, its ability to regulate sodium channel 1.7 …

Objective To examine the hypothesis that glial activation would regulate the expression of
the N-methyl-D-aspartate receptor subunit 1 (NR1) in the trigeminal subnucleus caudalis …

Objective: To investigate the association between the analgesic effect of non-steroidal
antiinflammatory drugs (NSAIDs) and sodium channel 1.7 (Nav1. 7) expression in the …

We previously demonstrated that sodium channel 1.7 (Nav1. 7) in trigeminal ganglion (TG)
was a critical factor in temporomandibular joint (TMJ) inflammation-induced …

Background. Women with temporomandibular disorders (TMDs) experience some
amelioration of pain during pregnancy. Progesterone increases dramatically and steadily …

The trigeminal ganglion (TG) refers to sensory neurons bodies that innervate the spinal cord
and peripheral axons that innervate teeth. The tetrodotoxin‐sensitive sodium (NA) channels …

Aims To investigate cellular changes in the spinal trigeminal nucleus (STN) and trigeminal
ganglion associated with trigeminal nociception mediated by inflammation in the …

Pulpitis causes significant changes in the peripheral nervous system, which induce
hyperalgesia. However, the relationship between neuronal activity and Nav1. 7 expression …

Background Trigeminal neuralgia is accompanied by severe mechanical, thermal and
chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion …