Erlotinib and gefitinib are quinazoline derivatives with antineoplastic properties. Usually,
intake of antineoplastic agents results in much a greater degree of oxidative stress, ie the …

Glipizide is an N-sulfonylurea compound used in the treatment of hyperglycemia in patients
with type 2 diabetes mellitus. In the present study, DFT-based computational methods and …

Quantum chemical calculations at the B3LYP/6–31G* level of theory were employed for the
structure-activity relationship and prediction of the antioxidant activity of edaravone and …

The thiazole ring closure of thiosemicarbazones with α-bromo-4-substituted acetophenones
was carried out to generate aminothiazole analogues (A1–A16). Experimental methods …

In this work, for the first time, we have investigated the structural and optoelectronic
properties of Erlotinib hydrochloride (C 22 H 24 N 3 O 4+· Cl−)(1) anticancer drug using DFT …

Synthetic antioxidants such as butylated hydroxyanisole (BHA) and butylated
hydroxytoluene (BHT) are found to be toxic, hence non-carcinogenic naturally occurring …

The antioxidant activity of molecules constitutes an important factor for the regulation of
redox homeostasis and reduction of the oxidative stress. Cells affected by oxidative stress …

Reactive oxygen species (ROS) are the most abundant intracellular oxidants produced by
various metabolic processes, and promote tumor metathesis. Herein, we report the …

Epidermal growth factor receptor (EGFR), a member of ErbB family of receptor tyrosine
kinases, is reportedly overexpressed in various types of human malignancies. Curcumin, a …

Flavonoids are natural compounds with antioxidant properties that have positive effects on
human health, which reduce toxic effects of reactive oxygen species (ROS) and partially …