Transgenic ruminants are a valuable resource for both animal breeding and biomedical
research. The development of transgenic breeding is proceeding slowly, because it suffers …

Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …

Since the generation of the first transgenic animal by Gordan and Ruddle, several methods
and procedures have been developed for the manipulation of the genome. This chapter …

The creation and development of genome editing (GE) technologies bring new opportunities
for the genetic engineering of farm mammals and poultry. The present review characterizes …

Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …

The Promises and Challenges of Precision Gene Editing in Animals of Agricultural Importance
Page 1 3 We live in changing times—it has always been that way. But, now the times are …

The first genetically modified large animals were developed in 1985 by microinjection to
increase the growth of agricultural livestock such as pigs. Since then, it has been a difficult …

Many types of mutant and genetically engineered strains have been produced in various
animal species. Their numbers have dramatically increased in recent years, with new strains …

Traditionally, genetic engineering in the pig was a challenging task. Genetic engineering of
somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically …

Targeted genome editing has opened new frontiers to study gene functions by introducing
alterations in the genome of an organism. The process incorporates deletion, insertion, or …