The discovery of sequence specific nucleases such as ZFNs, TALENs, and CRISPR/Cas9
has revolutionized genome editing. The CRISPR/Cas9 system has particularly emerged as …

The creation and development of genome editing (GE) technologies open new opportunities
in the genetic engineering of domestic mammals and poultry. In the present review, we have …

Genome editing represents a group of newly developed capabilities that allow nucleotide-
level targeting of genomic regions in a wide range of species. This chapter provides an …

As a new genetic engineering technology, gene editing can precisely modify the specific
gene sequence of the organism's genome. In the last 10 years, with the rapid development …

Since centuries, the traits for production and disease resistance are being targeted while
improving the genetic merit of domestic animals, using conventional breeding programs …

In the present era of high throughput sequencing, genomic databases are piling up new
sequences everyday with very little known about their functions and phenotypic effects …

Genome editing is a novel technology which enables targeted biological genome
modification. It can boost the transgenic efficiency, realize knockout livestock gene and fix …

Genome editing is the process of making targeted modifications to the genome at site-
specific locations. The most common methods for genome editing are sequence-specific …

Genome editing in large animals has tremendous practical applications, from more accurate
models for medical research through improved animal welfare and production efficiency …

Traditionally, genetic engineering in the pig was a challenging task. Genetic engineering of
somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically …