Abstract Interferon-alpha (IFN-alpha) can be considered as treatment of choice for patients
with chronic myeloid leukaemia (CML) in chronic phase. With this treatment major …

We used two-color fluorescence in situ hybridization (FISH) to detect BCR/ABL fusion in
interphase nuclei in bone marrow of 17 patients with chronic myeloid leukemia (CML) before …

There is a need for fast and sensitive methods to evaluate the response of patients with
chronic myeloid leukaemia (CML) to interferon‐α (IFN‐α) therapy to complement cytogenetic …

Using a highly sensitive fluorescence in situ hybridization method with probes for BCR and
ABL1 (D-FISH), we studied 37 paired sets of bone marrow and blood specimens, collected …

The effect of interferon-alpha (IFN) for chronic myeloid leukemia (CML) in the chronic phase
(CP) was retrospectively evaluated in comparison with that of busulfan (BU) or hydroxyurea …

Abstract Interferon‐α (IFN‐α) alone or in combination with cytostatic drugs can induce major
and durable cytogenetic responses in about 20 to 25% of chronic myeloid leukemia (CML) …

Cytogenetic analysis is considered pivotal for assessing the remission rate in CML patients
on IFN therapy. On the basis of general agreement, at least 25 metaphases should be …

Interferon-alpha produces a complete hematologic and cytogenetic remission in
approximately 20% of patients with chronic myelogenous leukemia (CML). In this study, we …

Interferon (IFN) alone or in combination with cytostatic drugs, can induce major and durable
cytogenetic remissions in chronic myelogenous leukaemia (CML) patients. Hypermetaphase …

In order to analyze the efficiency of interphase FISH for the detection and monitoring of Ph+
cells in chronic myelogenous leukemia (CML) under interferon (IFN) treatment, the following …