[HTML][HTML] Tumorigenic and immunogenic properties of induced pluripotent stem cells: a promising cancer vaccine

Y Qiao, OS Agboola, X Hu, Y Wu, L Lei - Stem Cell Reviews and Reports, 2020 - Springer
Induced pluripotent stem cells (iPSCs) are mainly characterized by their unlimited
proliferation abilities and potential to develop into almost any cell type. The creation of this …

[HTML][HTML] Potential of induced pluripotent stem cells for use in gene therapy: History, molecular bases, and medical perspectives

A Fus-Kujawa, B Mendrek, A Trybus, K Bajdak-Rusinek… - Biomolecules, 2021 - mdpi.com
Induced pluripotent stem cells (iPSCs) are defined as reprogrammed somatic cells
exhibiting embryonic stem cell characteristics. Since their discovery in 2006, efforts have …

Induced pluripotent stem cell as a new source for cancer immunotherapy

F Rami, H Mollainezhad… - Genetics research …, 2016 - Wiley Online Library
The immune system consists of cells, proteins, and other molecules that beside each other
have a protective function for the host against foreign pathogens. One of the most essential …

Induced pluripotent stem cells: The dragon awakens

W Han, Y Zhao, X Fu - BioScience, 2010 - academic.oup.com
Induced pluripotent stem cells (iPSCs) can be derived from many mouse and human
somatic cell types by forced expression of a small number of defined reprogramming factors …

[HTML][HTML] Pluripotent stem cells: cancer study, therapy, and vaccination

M Barati, M Akhondi, NS Mousavi… - Stem Cell Reviews and …, 2021 - Springer
Abstract Introduction Pluripotent stem cells (PSCs) are promising tools for modern
regenerative medicine applications because of their stemness properties, which include …

Induced pluripotent stem cell (iPSCs) and their application in immunotherapy

Z Jiang, Y Han, X Cao - Cellular & molecular immunology, 2014 - nature.com
The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …

[HTML][HTML] Engineering induced pluripotent stem cells for cancer immunotherapy

Y Zhou, M Li, K Zhou, J Brown, T Tsao, X Cen… - Cancers, 2022 - mdpi.com
Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

Generation of induced pluripotent stem cells from somatic cells

YD Sohn, JW Han, Y Yoon - … in molecular biology and translational science, 2012 - Elsevier
The technology for generation of induced pluripotent stem cell (iPSC) from somatic cells
emerged to circumvent the ethical and immunological limitations of embryonic stem cell …

[HTML][HTML] Inherent immunogenicity or lack thereof of pluripotent stem cells: implications for cell replacement therapy

A Chhabra - Frontiers in immunology, 2017 - frontiersin.org
Donor-specific induced pluripotent stem cells (iPSCs) offer opportunities for personalized
cell replacement therapeutic approaches due to their unlimited self-renewal potential and …

[HTML][HTML] Methods of induced pluripotent stem cells for clinical application

T Seki, K Fukuda - World journal of stem cells, 2015 - ncbi.nlm.nih.gov
Reprograming somatic cells using exogenetic gene expression represents a
groundbreaking step in regenerative medicine. Induced pluripotent stem cells (iPSCs) are …