Molecular cloning, expression, and developmental characterization of the murine retinoblastoma-related gene Rb2/p130.
The product of the retinoblastoma-related human gene Rb2/p130 is highly homologous with
the product of the retinoblastoma tumor suppressor gene (pRb) and Rb-related p107. this …
the product of the retinoblastoma tumor suppressor gene (pRb) and Rb-related p107. this …
[HTML][HTML] Molecular Cloning and Developmental Expression of Mouse p130, a Member of the Retinoblastoma Gene Family (∗)
G Chen, CT Guy, HW Chen, N Hu, YHPL Eva… - Journal of Biological …, 1996 - ASBMB
With sequence homology to the SV40 T antigen-binding domain of the retinoblastoma
protein (Rb), p107 and p130 constitute two additional members of the Rb family. To explore …
protein (Rb), p107 and p130 constitute two additional members of the Rb family. To explore …
Genomic structure of the human retinoblastoma-related Rb2/p130 gene.
A Baldi, V BocCIA, PP Claudio… - Proceedings of the …, 1996 - National Acad Sciences
The human Rb2/p130 gene shares many structural and functional features with the
retinoblastoma gene and the retinoblastoma-related p107 gene. In the present study, we …
retinoblastoma gene and the retinoblastoma-related p107 gene. In the present study, we …
The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cycle regulated
The Rb2/p130 protein has been shown to have a high sequence homology with the
retinoblastoma gene product (pRb), one of the most well‐characterized tumor suppressor …
retinoblastoma gene product (pRb), one of the most well‐characterized tumor suppressor …
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130
JH Dannenberg, L Schuijff, M Dekker… - Genes & …, 2004 - genesdev.cshlp.org
The retinoblastoma gene family consists of three genes: RB, p107, and p130. While loss of
pRB causes retinoblastoma in humans and pituitary gland tumors in mice, tumorigenesis in …
pRB causes retinoblastoma in humans and pituitary gland tumors in mice, tumorigenesis in …
p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107
The retinoblastoma tumor suppressor gene product, as well as its related protein p107, has
been shown clearly to exert its growth suppressive effects in a cell cycle dependent manner …
been shown clearly to exert its growth suppressive effects in a cell cycle dependent manner …
Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma
The retinoblastoma gene family consists of the tumor suppressor protein pRB and its two
relatives p107 and p130. These proteins have been implicated in the regulation of cell cycle …
relatives p107 and p130. These proteins have been implicated in the regulation of cell cycle …
Retinoblastoma-related protein pRb2/p130 and suppression of tumor growth in vivo
Background: The RB/p105 and p107 genes of the retinoblastoma family are tumor
suppressor genes whose proteins are inactivated by interaction with T-antigen proteins …
suppressor genes whose proteins are inactivated by interaction with T-antigen proteins …
Developmental expression of p107 mRNA and evidence for alternative splicing of the p107 (RBL1) gene product
KK Kim, MH Soonpaa, H Wang, LJ Field - Genomics, 1995 - Elsevier
Expression of p 107, a protein with homology to the retinoblastoma tumor suppressor (pRB),
was monitored during murine development. Northern blot tissue surveys identified two …
was monitored during murine development. Northern blot tissue surveys identified two …
Retinoblastoma protein family in cell cycle and cancer: a review
Two genes, p107 and Rb2/p130, are strictly related to RB, the most investigated tumor
suppressor gene, responsible for susceptibility to retinoblastoma. The products of these …
suppressor gene, responsible for susceptibility to retinoblastoma. The products of these …