In recent research, the tumor microenvironment has been shown to attract mesenchymal
stromal cells (MSCs), which is of particular interest due to its implications for cancer …

Tumor microenvironment (TME) is an active player in carcinogenesis and changes in its
composition modify cancer growth. Carcinoma-associated fibroblasts, bone marrow-derived …

Mesenchymal stem cells (MSCs) are multipotent progenitor cells capable of differentiating
into adipocytic, osteogenic, chondrogenic, and myogenic lineages. There is growing …

Head and neck cancer (HNC), a common malignancy worldwide, is associated with high
morbidity and mortality rates. Squamous cell carcinoma is the most common HNC type …

Objectives Bone mesenchymal stem cells (BMSCs) play critical roles in tumour
microenvironment. However, molecular mechanisms of how BMSCs to be recruited and …

The skeleton is a common site of cancer metastasis and malignancy with the resultant
lesions often being incurable. Interactions between metastatic cancer cells and the bone …

Skeletal metastasis is a serious complication of many primary cancers. A common feature of
tumor cells that metastasize to the bone marrow microenvironment is that they initiate a …

Bone invasion by head and neck squamous cell carcinoma (HNSCC) significantly impacts
tumor staging, treatment choice, prognosis, and quality of life. While HNSCC is known to …

Stromal cells in the tumor microenvironment (TME) can regulate the progression of
numerous types of cancer; however, the bone invasion of oral squamous cell carcinoma …

Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-
derived signals, such as inflammatory cytokines and growth factors. As a result, the …