Zinc, selenium and chromium co-supplementation improves insulin resistance by preventing hepatic endoplasmic reticulum stress in diet-induced gestational diabetes …

X Yao, R Liu, X Li, Y Li, Z Zhang, S Huang, Y Ge… - The Journal of nutritional …, 2021 - Elsevier
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications
and results in adverse outcomes for pregnant women and their offspring. Endoplasmic …

Transgenerational effects of zinc, selenium and chromium supplementation on glucose homeostasis in female offspring of gestational diabetes rats

X Yao, S Huang, Y Li, Y Ge, Z Zhang, J Ning… - The Journal of Nutritional …, 2022 - Elsevier
Clinical studies have demonstrated that maternal gestational diabetes mellitus (GDM)
increases the offspring's risk of developing glucose intolerance. Our previous study reported …

Effects of gestational diabetes mellitus and selenium deficiency on the offspring growth and blood glucose mechanisms of C57BL/6J mice

W Xu, J Gong, Y Chen, Y Chen, S Chen, Y Wu, Y He… - Nutrients, 2023 - mdpi.com
This study aimed to explore the effects and mechanisms of maternal gestational diabetes
mellitus (GDM) and selenium (Se) deficiency on the growth and glucose metabolism of …

The protective effect of zinc, selenium, and chromium on myocardial fibrosis in the offspring of rats with gestational diabetes mellitus

H Deng, X Yao, N Cui, S Huang, Y Ge, R Liu… - Food & Function, 2023 - pubs.rsc.org
The offspring of gestational diabetes mellitus (GDM) mothers are considered to be at the risk
of cardiovascular diseases due to intrauterine hyperglycemia exposure. Our previous study …

Protamine zinc insulin combined with sodium selenite improves glycometabolism in the diabetic KKAy mice

J Lu, W Ji, M Zhao, M Wang, W Yan, M Chen, S Ren… - Scientific Reports, 2016 - nature.com
Long-term, high dosage protamine zinc insulin (PZI) treatments produce adverse reactions.
The trace element selenium (Se) is a candidate for the prevention of diabetes due to anti …

Diabetes-induced hepatic pathogenic damage, inflammation, oxidative stress, and insulin resistance was exacerbated in zinc deficient mouse model

C Zhang, X Lu, Y Tan, B Li, X Miao, L Jin, X Shi… - PLoS …, 2012 - journals.plos.org
Objectives Zinc (Zn) deficiency often occurs in the patients with diabetes. Effects of Zn
deficiency on diabetes-induced hepatic injury were investigated. Methods Type 1 diabetes …

Selenium prevents inflammation in human placenta and adipose tissue in vitro: implications for metabolic diseases of pregnancy associated with inflammation

C Nguyen-Ngo, AV Perkins, M Lappas - Nutrients, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) and maternal obesity are significant metabolic
complications increasingly prevalent in pregnancy. Of major concern, both GDM and …

Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo …

Z Asemi, M Jamilian, E Mesdaghinia, A Esmaillzadeh - Nutrition, 2015 - Elsevier
Objective To our knowledge, no reports are available indicating the effects of selenium
supplementation on metabolic parameters, inflammatory factors, and oxidative stress in …

[HTML][HTML] Zinc supplementation prevented type 2 diabetes-induced liver injury mediated by the Nrf2-MT antioxidative pathway

L Yu, Y Liu, Y Jin, T Liu, W Wang, X Lu… - Journal of Diabetes …, 2021 - hindawi.com
Zinc is an essential trace element that is often reduced under the type 1 diabetic condition.
Previous studies demonstrated that zinc deficiency enhanced type 1 diabetes-induced liver …

[PDF][PDF] Impact of maternal chromium restriction on glucose tolerance, plasma insulin and oxidative stress in WNIN rat offspring

IJN Padmavathi, KR Rao… - Journal of molecular …, 2011 - researchgate.net
Robust evidence suggests that nutritional insult during fetal development could program the
offspring to glucose intolerance, impaired insulin response and insulin resistance (IR) …