Interleukin-8 and the neutrophil response to mucosal gram-negative infection.

WW Agace, SR Hedges, M Ceska… - The Journal of clinical …, 1993 - Am Soc Clin Investig
Urinary tract infections activate a mucosal inflammatory response, which includes cytokine
secretion and neutrophil influx. The mechanisms involved in the neutrophil influx have not …

Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria

S Hedges, P Anderson, G Lidin-Janson… - Infection and …, 1991 - Am Soc Microbiol
Intravesical inoculation of patients with Escherichia coli provided an opportunity to examine
the interleukin-6 (IL-6) response to a gram-negative bacterial urinary tract infection in …

Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro

S Hedges, M Svensson, C Svanborg - Infection and immunity, 1992 - Am Soc Microbiol
This study demonstrated that epithelial cell lines secrete interleukin-6 (IL-6) in response to
stimulation with gram-negative bacteria. Human epithelial cell lines of urinary tract origin (A …

Elevated interleukin-8 levels in the urine of patients with urinary tract infections

YC Ko, N Mukaida, S Ishiyama, A Tokue… - Infection and …, 1993 - Am Soc Microbiol
Pyuria is one of the main features of urinary tract infections (UTI). Nevertheless, the
mechanism of polymorphonuclear leukocyte (PMN) recruitment into the urine remains to be …

Local cytokine production in a murine model of Escherichia coli pyelonephritis.

HS Rugo, P O'hanley, AG Bishop… - The Journal of …, 1992 - Am Soc Clin Investig
Cytokines may play an important role in the regulation of host defense against local bacterial
infections. We have evaluated the local production of cytokines in a BALB/c mouse model of …

Comparison of urine and serum concentrations of Interleukin-6 in women with acute pyelonephritis or asymtomatic bacteriuria

S Hedges, K Stenqvist, G Lidin-Janson… - Journal of Infectious …, 1992 - academic.oup.com
The mucosal and systemic interleukin-6 (IL-6) response to urinary tract infection was
analyzed in women with acute pyelonephritis or asymptomatic bacteriuria. Urine and serum …

Interleukin-6 and disease severity in patients with bacteremic and nonbacteremic febrile urinary tract infection

G Otto, JH Braconier, A Andreasson… - The Journal of …, 1999 - academic.oup.com
Abstract An interleukin-6 (IL-6) response was detected in 81 patients with febrile urinary tract
infections (UTIs). Bacteremic patients (n= 24) had higher serum IL-6 at inclusion and …

Interleukin (IL)-6 and IL-8 in children with febrile urinary tract infection and asymptomatic bacteriuria

M Benson, U Jodal, W Agace… - Journal of Infectious …, 1996 - academic.oup.com
Urine and serum interleukin (IL)-6 and IL-8responseswere higher in children with febrile
urinary tract infection (n= 61) than in those with asymptomatic bacteriuria (n= 39). By …

Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells.

FR Jirik, TJ Podor, T Hirano, T Kishimoto… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
The interaction between human endothelial cells and leukocytes during immunologic and
inflammatory responses is in part mediated through the release of soluble mediators. We …

Interleukin 6 response to urinary tract infection in childhood

M Benson, U Jodal, A Andreasson… - The Pediatric …, 1994 - journals.lww.com
This study analyzed the interleukin 6 (IL-6) response in 114 children with suspected urinary
tract infection (UTI). Urine and serum samples were obtained at the time of enrollment. There …