Interleukin-10 is produced during incubation of human whole blood with bacterial
lipopolysaccharide (LPS) and down-regulates tumour necrosis factor-alpha production in …

The role of lipopolysaccharide (LPS) as an activator of human monocyte interleukin-1 (IL-1)
synthesis and secretion has been examined in this study. The results demonstrate that when …

Recent studies have suggested that intestinal epithelial cells demonstrate some of the
functions associated with immune competent cells. Based on these observations, we …

Immunologic complications of chronic renal failure are associated with the overproduction of
proinflammatory cytokines by monocytes. This is partly due to renal failure itself but is further …

Abstract Interleukin (IL)-10 is a novel cytokine produced by a variety of cells, including
monocytes/macrophages, upon exposure to lipopolysaccharide (LPS). Recent observations …

IL-8 is a major human neutrophil chemoattractant at mucosal infection sites. This study
examined the CXC chemokine response to mucosal infection, and, specifically, the role of …

Localized tissue disruption quickly elicits systemic alterations in the biochemical,
physiologic, and immunologic status of the host (1–3). The hypothesis that a circulating …

The production of several cytokines such as interleukin (IL)-1 in gastric mucosa is increased
in subjects infected with Helicobacter pylori, a bacterium associated with ulcer recurrence …

We report that TNF, IL-6, and IFN-alpha/beta are produced by mice during either sublethal or
lethal Listeria monocytogenes infections. The quantities of these cytokines in infected …

We describe a 15-yr-old girl with recurrent bacterial infections who is refractory to the effects
of LPS in vivo and in vitro and IL-1 in vitro. Intravenous challenge of the patient with …