The interaction between human endothelial cells and leukocytes during immunological and
inflammatory responses is in part mediated through the release of soluble mediators. We …

Vascular endothelial cells (EC) play an important role in the emigration from the blood of the
mononuclear cells that participate in the chronic inflammatory response. Because EC …

Interleukin-1 (IL-1) is a polypeptide cytokine that mediates many physiological responses to
infection and inflammation and is a growth factor for certain mammalian cells. Virulent and …

Experimental bacterial infection of the dermis induced with gram-negative microorganisms is
associated with an acute inflammatory reaction, which represents the principal local defense …

We have examined the ability of rat mesangial cells to regulate neutral proteinase
production in vitro. Mesangial cells constitutively produced gelatinase when cultured in …

1. We studied neutrophil-activating peptide-1/interleukin-8 in inflammatory bowel disease. 2.
Mucosal levels of neutrophil-activating peptide-1/interleukin-8 were significantly higher in …

The concentration of myeloperoxidase, a neutrophil granule constituent, was measured in
the perfusion fluid from sigmoid and rectal segments in patients with ulcerative colitis. The …

We have previously shown that IL-6 is a major cytokine in the serum of mice infected with the
intracellular bacterium Listeria monocytogenes, and that injection of rIL-6 before, but not …

Serum samples from patients with meningococcal disease were examined for the presence
of IL-6, TNF-alpha, and LPS. Median serum concentration of IL-6 was 1,000 times higher in …

IL-8, a cytokine known for its potent and specific neutrophil activation and chemoattractant
properties, has been recently detected in the circulation during septic shock, endotoxemia …