Abstract Interleukin 1 (IL-1) alters several potentially pathogenic endothelial cell (EC)
functions. The authors report here that recombinant human IL-1 (rIL-1) alpha (0.1 to 10 …

In this study we have examined the effects of interleukin 10 (IL-10) on polymorphonuclear
leukocytes (PMN), and found that it is a potent inhibitor of tumor necrosis factor (TNF), IL-1 …

This study investigates the effect of interferons on the induction of human monocyte
secretion of interleukin-1 (IL-1) activity by lipopolysaccharides (LPS). Monocytes do not …

The role of interleukin 1 (IL 1) in 16 patients with sepsis and 16 normal controls was
investigated. Thymocyte costimulation was used to assay in vitro IL 1 levels produced by …

Background: Interleukin-18 (IL-18) is a mediator of ischemic acute tubular necrosis (ATN) in
mice. Methods: IL-18 was measured in human urine to determine whether it might serve as a …

The capacity of human cultured mesangial cells to produce soluble factors potentially
relevant for mechanisms of inflammation and immunity at the glomerular site was analyzed …

Abstract Interferon-gamma (IFN-gamma) is a macrophage-activating factor that has also
been shown to act on endothelial cells (EC). Interleukin 1 (IL 1), first described as a …

During acute inflammation, the first line of cellular response for host defense is the
neutrophil. In addition to the historic role of the neutrophil as a phagocyte, recent studies …

The nature of the endogenous mediators that down-regulate and curtail the exodus of
neutrophils into local acute inflammatory sites is unknown. In the present report, interleukin …

Interleukin 1 (IL-1) may be a key mediator of inflammation and tissue damage in
inflammatory bowel disease (IBD). In rabbits with immune complex-induced colitis, IL-1 …