We recently identified a novel cDNA encoding a retinoblastoma protein (pRb)-associated
protein. It was named RBP95, which was composed of 838 amino acid residues with a …

The retinoblastoma protein (pRb) functions as a critical master regulator in cell cycle
regulation, which is an important cell-regulatory process, through its interaction with various …

We have previously isolated cDNA of a novel protein (RBQ-1, HGMW-approved symbol
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …

A 2860-bp cDNA was isolated from a human fetal brain cDNA library by high throughput
cDNA sequencing, which encodes a putative protein with 186 amino acids. The putative …

The retinoblastoma susceptibility gene product pRb restricts cellular proliferation by affecting
gene expression by all three classes of nuclear RNA polymerases. To elucidate the …

Retinoblastoma protein (pRb) functions as a tumor suppressor, and certain proteins are
known to bind to pRb in the C-terminal region. Although the N-terminal region of pRb may …

Even though the retinoblastoma gene is one of the best-studied tumor suppressor genes,
little is known about its functional role. Like all tumor suppressor gene products, the …

We have isolated cDNA and genomic clones for the human retinoblastoma binding protein 1
(RBP1) gene, and have identified alternative splicing of RBP1 clustered within a 207 …

Over the past 10 years, tumor suppressor genes involved in many human malignancies
have been isolated. The retinoblastoma gene was the first such tumor suppressor gene to …

In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of
retinoblastoma protein (pRb)-activity. Members of the previously described family of …