Role of complement in induction of antibody production in vivo: effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent …

MB Pepys - The Journal of experimental medicine, 1974 - ncbi.nlm.nih.gov
In an in vivo study in mice, suppression by the C3-cleaving protein of cobra venom (CoF),
and other C3-reactive agents (zymosan, aggregated IgG, anti-C3 antibodies, and type III …

Complement-dependent B-cell activation by cobra venom factor and other mitogens?

P Dukor, G Schumann, RH Gisler, M Dierich… - The Journal of …, 1974 - rupress.org
It has been proposed that two distinct signals are required for the triggering of the precursors
of antibody-forming bone marrow-derived cells (B cells):(a) the binding of antigen or of a …

[引用][C] Role of complement in the induction of immunological responses

MB Pepys - Immunological reviews, 1976 - Wiley Online Library
Abbreviations: CoF, cobra factor, the complement activating protein of cobra venom; SRBC,
sheep red blood cells; CRL, complement receptor lymphocyte (s); DNP and TNP, dinitro-and …

The role of C3 in the immune response

A Erdei, G Fust, J Gergely - Immunology today, 1991 - cell.com
The complement system, particularly the third component, plays an important modulatory
role in the inductive phase of the immune response. As discussed here by Anna Erdei and …

Role of complement in induction of the allergic response

MB Pepys - Nature New Biology, 1972 - nature.com
ALTHOUGH there is substantial evidence for cell cooperation in the induction of various
allergic responses, there are few data concerning the mechanisms of the cellular …

The action of human C3 in soluble or cross‐linked form with resting and activated murine B lymphocytes

A Erdei, F Melchers, T Schulz… - European journal of …, 1985 - Wiley Online Library
The third component of complement C3 has been implied in the stimulation of B
lymphocytes to proliferation and maturation for Ig secretion. We have reinvestigated the …

The alternate pathway of complement activation: the role of C3 and its inactivator (KAF)

PAE Nicol, PJ Lachmann - Immunology, 1973 - ncbi.nlm.nih.gov
The immunochemical depletion from serum of C3b inactivator (KAF) has been performed
using purified F (ab′) 2 antibody. In vitro KAF depletion leads to spontaneous activation of …

A simple rosette assay for demonstration of complement receptor sites using complement‐coated zymosan beads

CH Huber, H Wigzell - European Journal of Immunology, 1975 - Wiley Online Library
In the present article we describe a simple rosette assay for detection of C3 receptor‐
bearing B lymphocytes with complement (C)‐coated zymosan (Zy) beads. Zy coated with …

Two different complement receptors on human lymphocytes: one specific for C3b and one specific for C3b inactivator-cleaved C3b

GD Ross, MJ Polley, EM Rabellino… - The Journal of …, 1973 - rupress.org
In the present study it was shown that normal peripheral lymphocytes have two different
complement receptors: one for C3b (the immune adherence receptor) and one for C3b …

The C3-activator system: an alternate pathway of complement activation

O Gotze, HJ Müller-Eberhard - The Journal of experimental medicine, 1971 - rupress.org
Evidence has accumulated indicating the existence of a second complement activation
mechanism which is functionally analogous to C1, C2, and C4. The noncomplement protein …