Even though the importance of epigenetics was first recognized in light of its role in tissue
development, an increasing amount of evidence has shown that it also plays an important …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …

Epigenetics is one of the key areas of future research that can elucidate how genomes work.
It combines genetics and the environment to address complex biological systems such as …

In the first half of the twentieth century, developmental biology and genetics were separate
disciplines. The word epigenetics was coined by Waddington to link the two fields …

The spatial arrangement and three-dimensional structure of DNA in the nucleus is controlled
through the interdigitation of DNA binding proteins such as histones and their modifiers, the …

Epigenetic modification can mediate environmental influences on gene expression and can
modulate the disease risk associated with genetic variation. Epigenetic analysis therefore …

DNA methylation is one of the most intensely studied epigenetic modifications in mammals.
In normal cells, it assures the proper regulation of gene expression and stable gene …

The prospect of finding epigenetic risk factors for complex diseases would be greatly
enhanced if DNA from existing biobanks, which is generally extracted from whole blood …

DNA methylation is a biochemical process where a DNA base, usually cytosine, is
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …