Genome-wide analysis of DNA methylation dynamics during early human development
H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
DNA methylation is globally reprogrammed during mammalian preimplantation
development, which is critical for normal development. Recent reduced representation …
development, which is critical for normal development. Recent reduced representation …
DNA methylation landscapes of human fetal development
RC Slieker, MS Roost, L van Iperen… - PLoS …, 2015 - journals.plos.org
Remodelling the methylome is a hallmark of mammalian development and cell
differentiation. However, current knowledge of DNA methylation dynamics in human tissue …
differentiation. However, current knowledge of DNA methylation dynamics in human tissue …
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Background Changes in DNA methylation in the mammalian genome during development
are frequent events and play major roles regulating gene expression and other …
are frequent events and play major roles regulating gene expression and other …
Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis
O Bogdanović, SW Long, SJ van Heeringen… - Genome …, 2011 - genome.cshlp.org
DNA methylation is a tightly regulated epigenetic mark associated with transcriptional
repression. Next-generation sequencing of purified methylated DNA obtained from early …
repression. Next-generation sequencing of purified methylated DNA obtained from early …
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …
understanding the evolution of different cellular phenotypes. While studies have confirmed …
DNA methylation reprogramming of functional elements during mammalian embryonic development
DNA methylation plays important roles during development. However, the DNA methylation
reprogramming of functional elements has not been fully investigated during mammalian …
reprogramming of functional elements has not been fully investigated during mammalian …
Spatiotemporal DNA methylome dynamics of the developing mouse fetus
Cytosine DNA methylation is essential for mammalian development but understanding of its
spatiotemporal distribution in the developing embryo remains limited,. Here, as part of the …
spatiotemporal distribution in the developing embryo remains limited,. Here, as part of the …
Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
Mouse embryos acquire global DNA methylation of their genome during implantation.
However the exact roles of DNA methyltransferases (DNMTs) in embryos have not been …
However the exact roles of DNA methyltransferases (DNMTs) in embryos have not been …
Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing
DNA methylation is crucial for a wide variety of biological processes, yet no technique
suitable for the methylome analysis of DNA methylation at single-cell resolution is available …
suitable for the methylome analysis of DNA methylation at single-cell resolution is available …
Single-cell DNA methylome sequencing of human preimplantation embryos
DNA methylation is a crucial layer of epigenetic regulation during mammalian embryonic
development,–. Although the DNA methylome of early human embryos has been analyzed …
development,–. Although the DNA methylome of early human embryos has been analyzed …
相关搜索
- early human development
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- changes in dna methylation
- sequence conservation dna methylation
- early embryos stem cells
- human fetal development
- temporal uncoupling dna methylome
- transcriptional repression dna methylome
- dna methylome dynamics