Transcriptional regulation of adipogenesis

PM de Sá, AJ Richard, H Hang… - Comprehensive …, 2011 - Wiley Online Library
Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …

Transcriptional and epigenomic regulation of adipogenesis

JE Lee, H Schmidt, B Lai, K Ge - Molecular and cellular biology, 2019 - Taylor & Francis
Understanding adipogenesis, the process of adipocyte development, may provide new ways
to treat obesity and related metabolic diseases. Adipogenesis is controlled by coordinated …

[HTML][HTML] Hormonal signaling and transcriptional control of adipocyte differentiation

RF Morrison, SR Farmer - The Journal of nutrition, 2000 - Elsevier
Recent advances regarding the biology of adipose tissue have identified the adipocyte as
an important mediator in many physiologic and pathologic processes regarding energy …

Transcriptional activation of adipogenesis

Z Wu, P Puigserver, BM Spiegelman - Current opinion in cell biology, 1999 - Elsevier
Studies from the past several years have revealed that adipogenesis is controlled by an
interplay of transcription factors, including members of the CCAAT/enhancer binding protein …

Adipocyte differentiation: a transcriptional regulatory cascade

RP Brun, JB Kim, E Hu, S Altiok… - Current opinion in cell …, 1996 - Elsevier
The adipose cell is now known to play a complex role in energy homeostasis, energy
storage and signaling to other tissues concerning the state of energy balance. The past few …

[HTML][HTML] Brown vs white adipocytes: The PPARγ coregulator story

A Koppen, E Kalkhoven - FEBS letters, 2010 - Elsevier
The development of adipose tissue is a process which involves the concerted cooperation of
numerous transcription factors together with their coactivators and corepressors. The …

New developments in adipogenesis

MI Lefterova, MA Lazar - Trends in Endocrinology & Metabolism, 2009 - cell.com
The obesity epidemic has focused attention on adipose tissue and the development of fat
cells (ie adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated …

Adipogenesis: a complex interplay of multiple molecular determinants and pathways

MA Ambele, P Dhanraj, R Giles, MS Pepper - International journal of …, 2020 - mdpi.com
The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

Transcriptional factors that promote formation of white adipose tissue

UA White, JM Stephens - Molecular and cellular endocrinology, 2010 - Elsevier
Adipocytes are highly specialized cells that play a major role in energy homeostasis in
vertebrate organisms. Excess adipocyte size or number is a hallmark of obesity, which is …

Modulating the transcriptional control of adipogenesis

TM Loftus, MD Lane - Current opinion in genetics & development, 1997 - Elsevier
Current evidence indcates that much of the regulation of adipocyte differentiation serves to
modulate a common adipogenic transcriptional control pathway, comprising members of the …