Quantitative competitive reverse transcriptase-polymerase chain reaction for BCR-ABL on Philadelphia-negative leukaphereses allows the selection of low …

MT Corsetti, E Lerma, A Dejana, P Basta, R Ferrara… - Leukemia, 1999 - nature.com
Abstract The Philadelphia (Ph) translocation t (9; 22) results in the creation of the BCR-ABL
gene, which is now regarded as central to the mechanism that underlies the chronic phase …

Detection of Philadelphia chromosome-positive cells by the polymerase chain reaction following bone marrow transplant for chronic myelogenous leukemia

MS Roth, JH Antin, EL Bingham, D Ginsburg - 1989 - ashpublications.org
Sixteen patients treated by allogeneic bone marrow transplantation (BMT) for chronic
myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for …

The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive …

AH Elmaagacli, DW Beelen, B Opalka, S Seeber… - Annals of …, 2000 - Springer
The use of the real-time reverse-transcription polymerase-chain reaction (RT-PCR) method
to quantify BCR-ABL transcripts before and after allogeneic transplant was prospectively …

[PDF][PDF] Peripheral blood progenitor cells mobilized early at diagnosis in patients with chronic myelogenous leukemia contain very low amounts of BCR-ABL transcripts

MT Corsetti, M Podesta, E Lerma, GL Pira, F Manca… - Leukemia, 1998 - researchgate.net
In the last 8 years, in chronic myelogenous leukemia (CML) patients without a suitable donor
for allografting, we demonstrated that it was possible to mobilize Ph-negative peripheral …

Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous …

R Delage, RJ Soiffer, K Dear, J Ritz - 1991 - ashpublications.org
In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …

BCR-ABL expression in different subpopulations of functionally characterized Ph+ CD34+ cells from patients with chronic myeloid leukemia

V Maguer-Satta, AL Petzer, AC Eaves, CJ Eaves - 1996 - ashpublications.org
In patients with chronic myeloid leukemia (CML), the leukemic (BCR-ABL+/Ph+) clone
typically includes cells belonging to all of the myeloid lineages and frequently some B cells …

Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL …

MK Gordon, D Sher, T Karrison, P Kebriaei… - Leukemia & …, 2008 - Taylor & Francis
Imatinib mesylate is the initial therapy of choice for chronic myeloid leukemia in chronic
phase (CML-CP), but in some patients, the disease becomes resistant to imatinib …

Apparent decrease and elimination of BCR/ABL mRNA-expressing residual cells in patients with chronic myelogenous leukemia after allogeneic bone marrow …

W Lange, R Herkert, J Finke, U Ragoczy, W Siegert… - Annals of …, 1991 - Springer
A modified two-step polymerase chain reaction (PCR) was used for the amplification of
BCR/ABL mRNA in 16 patients with Philadelphia chromosomepositive (Ph+) chronic …

Mobilization of hematopoietic progenitors in patients with chronic myeloid leukemia

SFT Thijsen, GJ Schuurhuis… - Bone marrow …, 1997 - nature.com
Although the mobilization and harvesting of Philadelphia chromosome-negative progenitors
has been proven feasible by a number of groups, it is not clear which techniques should be …

Peripheral blood is a source of BCR-ABL-negative pre-progenitors in early chronic phase chronic myeloid leukemia

ID Lewis, DN Haylock, S Moore, LB To, TP Hughes - Leukemia, 1997 - nature.com
Manipulation of autologous bone marrow cells (BM) for transplantation in chronic myeloid
leukemia (CML) to enrich for normal cells is a novel approach that may improve survival for …