Cartilage lesions fail to heal spontaneously, leading to the development of chronic
conditions which worsen the life quality of patients. Three-dimensional scaffold-based …

There is no long-term treatment strategy for young and active patients with cartilage defects.
Early and effective joint preserving treatments in these patients are crucial in preventing the …

Objective Treatment of chondral injury is clinically challenging. Available chondral
repair/regeneration techniques have significant shortcomings. A viable and durable tissue …

Bioprinting is a growing field with significant potential for developing engineered tissues with
compositional and mechanical properties that recapitulate healthy native tissue. Much of the …

Three-dimensional (3D) bioprinting techniques can be used for the fabrication of
personalized, regenerative constructs for tissue repair. The current article provides insight …

Chondral and osteochondral lesions represent one of the most challenging and frustrating
scenarios for the orthopedic surgeon and for the patient. The lack of therapeutic strategies …

Cartilage is an avascular tissue with extremely limited self-regeneration capabilities. At
present, there are no existing treatments that effectively stop the deterioration of cartilage or …

The field of regeneration for functional cartilage has progressed tremendously. Conventional
approaches for regenerating the damaged tissue based on integrated manufacturing are …

In regenerative medicine and tissue engineering, the possibility to:(I) customize the shape
and size of scaffolds,(II) develop highly mimicked tissues with a precise digital control,(III) …

Articular cartilage defects are one of the most common clinical diseases of bone articulation.
Early repair of damaged joint cartilage can effectively stop the progression of arthritis and …