Childhood trauma and dissociation in female patients with schizophrenia spectrum disorders: an exploratory study

I Schäfer, T Harfst, V Aderhold, P Briken… - The Journal of …, 2006 - journals.lww.com
The few studies that have investigated the relationship between trauma and dissociative
symptoms in patients with schizophrenia have not assessed the role of the severity of …

Adolescent stress as a driving factor for schizophrenia development—a basic science perspective

FV Gomes, AA Grace - Schizophrenia bulletin, 2017 - academic.oup.com
Schizophrenia has been associated with heightened stress responsivity in adolescence that
precedes onset of psychosis. We now report that multiple stressors during adolescence in …

Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia

E Walker, V Mittal, K Tessner - Annu. Rev. Clin. Psychol., 2008 - annualreviews.org
Diathesis-stress models of schizophrenia and other psychotic disorders have dominated
theorizing about etiology for over three decades. More recently, with advances in our …

Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?

M Aas, NE Steen, I Agartz, SR Aminoff, S Lorentzen… - Psychiatry …, 2012 - Elsevier
Schizophrenia spectrum and bipolar disorder are characterized by high levels of childhood
trauma as well as of cognitive dysfunction. Our aim is to investigate the association between …

Childhood trauma and schizotypy: a systematic literature review

T Velikonja, HL Fisher, O Mason… - Psychological medicine, 2015 - cambridge.org
Background. Schizotypy is a complex concept, commonly defined as a genetic vulnerability
to schizophrenia that falls on a continuum between healthy variation and severe mental …

The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological …

M Pruessner, AE Cullen, M Aas, EF Walker - … & Biobehavioral Reviews, 2017 - Elsevier
Over the past decade, our understanding of the role of stress in serious mental illness has
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …

Childhood trauma and clinical high risk for psychosis

RL Loewy, S Corey, F Amirfathi, S Dabit, D Fulford… - Schizophrenia …, 2019 - Elsevier
As a risk factor for psychosis, childhood trauma rates are elevated in the clinical-high-risk
(CHR) syndrome compared to the general population. However, it is unknown whether …

Differential effects of childhood abuse and neglect: mediation by posttraumatic distress in neurotic disorder and negative symptoms in schizophrenia?

M Vogel, J Meier, S Grönke, M Waage, W Schneider… - Psychiatry …, 2011 - Elsevier
Dissociation, though understood as a response to trauma, lacks a proven etiology. The
assumption of a dose–response relationship between trauma, dissociation and …

Childhood trauma, brain structure and emotion recognition in patients with schizophrenia and healthy participants

KI Rokita, L Holleran, MR Dauvermann… - Social cognitive and …, 2020 - academic.oup.com
Childhood trauma, and in particular physical neglect, has been repeatedly associated with
lower performance on measures of social cognition (eg emotion recognition tasks) in both …

Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization

OD Howes, R McCutcheon - Translational psychiatry, 2017 - nature.com
An interaction between external stressors and intrinsic vulnerability is one of the longest
standing pathoaetiological explanations for schizophrenia. However, novel lines of evidence …