Abstract Aim: Astronauts return to Earth with reduced red cell masses and hypovolaemia.
Not surprisingly, when they stand, their heart rates may speed inordinately, their blood …

Astronauts returning from space have reduced red blood cell masses, hypovolaemia and
orthostatic intolerance, marked by greater cardio–acceleration during standing than before …

When astronauts return to Earth and stand, their heart rates may speed inordinately, their
blood pressures may fall, and some may experience frank syncope. We studied brief …

Introduction Despite decades of study, a clear understanding of autonomic nervous system
activity in space remains elusive. Differential interpretation of fundamental data has driven …

Cardiac output is increased by some 18% by weightlessness during the initial week of
spaceflight compared to upright standing or sitting on the ground and more so during the …

Orthostatic intolerance is common when astronauts return to Earth: after brief spaceflight, up
to two‐thirds are unable to remain standing for 10 min. Previous research suggests that …

We studied three Russian cosmonauts to better understand how long-term exposure to
microgravity affects autonomic cardiovascular control. We recorded the electrocardiogram …

Physiologists have always been challenged by the adjustments of the human body to hostile
environments. The set of papers in this issue of The Journal of Physiology (Cox et al. 2002; …

Spaceflight is associated with decreased orthostatic tolerance after landing. Short-duration
spaceflight (4–5 days) impairs one neural mechanism: the carotid baroreceptor-cardiac …

After spaceflight, astronauts sometimes suffer a variable degree of reduced orthostatic
tolerance. Although many studies have addressed this problem, many aspects remain …