MicroRNAs, a class of small non-coding RNAs, are believed to regulate several biological
pathways and processes and are implicated in several diseases. They mostly regulate the …

MicroRNAs, a class of small noncoding RNAs, are implicated in controlling a variety of
biological processes. We have shown that leucine deprivation suppresses lipogenesis by …

Background: Hepatic expression of microRNA-107 is ubiquitously upregulated in various
metabolic diseases. In our previous study, we had demonstrated that fatty acid synthase …

Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation and is
presently the most common chronic liver disease. However, the mechanisms underlying the …

Emerging studies have demonstrated that microRNAs (miRs) are profoundly involved in non-
alcoholic fatty liver disease (NAFLD) and related metabolic diseases. Previously, we …

AIM: To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …

In a microarray study, we found that hepatic miR-291b-3p was significantly increased in
leptin-receptor-deficient type 2 mice (db/db), a mouse model of diabetes. The function of miR …

MicroRNAs are potential therapeutic targets for metabolic diseases. Here, miR-1224-5p was
highly expressed in the livers of mice fed a high-fat diet (HFD) and in obese (ob/ob) mice. To …

Abstract microRNAs (miRNAs or miRs) are small non-coding RNAs that are involved in post-
transcriptional regulation of their target genes in a sequence-specific manner. Emerging …

Non-alcoholic fatty liver disease (NAFLD) affects obesity-associated metabolic syndrome,
which exhibits hepatic steatosis, insulin insensitivity and glucose intolerance. Previous …