The emerging role of estrogens in thyroid redox homeostasis and carcinogenesis

CC Faria, MS Peixoto, DP Carvalho… - … medicine and cellular …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are the most critical class of free radicals or reactive
metabolites produced by all living organisms. ROS regulate several cellular functions …

Metabolic alterations of thyroid cancer as potential therapeutic targets

D Ciavardelli, M Bellomo, A Consalvo… - BioMed research …, 2017 - Wiley Online Library
Thyroid cancer (TC) is the most frequent endocrine tumor with a growing incidence
worldwide. Besides the improvement of diagnosis, TC increasing incidence is probably due …

Papillary thyroid carcinoma: A malignant tumor with increased antioxidant defense capacity

BR Rovcanin, KR Gopcevic, DL Kekic… - The Tohoku journal of …, 2016 - jstage.jst.go.jp
Papillary thyroid carcinoma (PTC) is the commonest thyroid malignancy worldwide for which
the radiation exposure is the most influential risk factor. The levels of oxidative stress in PTC …

A comparative study of the oxidative profile in Graves' disease, Hashimoto's thyroiditis, and papillary thyroid cancer

S Lassoued, M Mseddi, F Mnif, M Abid… - Biological trace element …, 2010 - Springer
The aim of this study was to evaluate and compare the oxidative profiles of three thyroid
disorders: Graves' disease (GD), Hashimoto thyroiditis (HT), and papillary thyroid cancer …

Genomic evidence of reactive oxygen species elevation in papillary thyroid carcinoma with Hashimoto thyroiditis

JW Yi, JY Park, JY Sung, SH Kwak, J Yu… - Endocrine …, 2015 - jstage.jst.go.jp
Elevated levels of reactive oxygen species (ROS) have been proposed as a risk factor for
the development of papillary thyroid carcinoma (PTC) in patients with Hashimoto thyroiditis …

Differentiated thyroid cancer—personalized therapies to prevent overtreatment

M Luster, T Weber, FA Verburg - Nature Reviews Endocrinology, 2014 - nature.com
The concept of individualized therapy is rapidly gaining recognition in the management of
patients with differentiated thyroid cancer (DTC). This Review provides an overview of the …

Heterogeneity of thyroid cancer

E Chmielik, D Rusinek, M Oczko-Wojciechowska… - Pathobiology, 2018 - karger.com
There are 5 main histological types of thyroid cancers (TCs): papillary, follicular (also known
as differentiated), poorly differentiated, anaplastic (the most aggressive form), and medullary …

[HTML][HTML] Multi-omics signatures and translational potential to improve thyroid cancer patient outcome

M Boufraqech, N Nilubol - Cancers, 2019 - mdpi.com
Recent advances in high-throughput molecular and multi-omics technologies have
improved our understanding of the molecular changes associated with thyroid cancer …

Role of tissue antioxidant defence in thyroid cancers

GR Sadani, GD Nadkarni - Cancer letters, 1996 - Elsevier
Reactive oxygen species (ROS), consisting mainly of superoxide, hydrogen peroxide and
hydroxyl radical, have been implicated in many diseases including cancer. ROS have been …

[HTML][HTML] Improving quality of life in patients with differentiated thyroid cancer

P Pace-Asciak, JO Russell, RP Tufano - Frontiers in Oncology, 2023 - frontiersin.org
Well differentiated thyroid cancer is a common malignancy diagnosed in young patients. The
prognosis tends to be excellent, so years of survivorship is expected with low risk disease …