Natural killer (NK) cells are the main innate immune cells, and have powerful antitumor
activity in vitro, but NK cells based immunotherapy does not often get satisfactory results in …

Natural killer (NK) cells are considered a promising strategy for cancer treatment. Various
methods for large-scale NK cell expansion have been developed, but they should guarantee …

Aim To obtain sufficient numbers of pure and activated human primary NK cells for potential
clinical application. Methods PBMC based ex vivo expansion of natural killer cells was set …

Preserving the activities of natural killer (NK) cells in human peripheral blood mononuclear
cells (PBMCs) after ex vivo expansion and activation is critical for NK cell-based therapy …

Natural killer cells are progressively considered as medical tools for cancer immunotherapy.
The development of applicable methods to generate large numbers of functional NK cells is …

Natural killer (NK) cells can detect and kill tumor cells and infusion of NK cells to cancer
patients may be a promising option to treat cancer. In this context, ex vivo expansion is used …

Ex vivo-expanded, allogeneic natural killer (NK) cells can be used for the treatment of
various types of cancer. In allogeneic NK cell therapy, NK cells from healthy donors must be …

Natural killer (NK) cells can kill a wide range of cancer cells and are a promising tool for cell
therapy of cancer. NK cells cytotoxicity is regulated by a balance between stimulatory and …

Natural killer (NK) cells are promising antitumor effector cells, but the generation of sufficient
NK cell numbers for adoptive immunotherapy remains challenging. Therefore, we …

Natural killer (NK) cells are a promising tool for the use in adoptive immunotherapy, since
they efficiently recognize and kill tumor cells. In this context, ex vivo cultivation is an …