[HTML][HTML] Antibiofilm peptides: overcoming biofilm-related treatment failure
Health leaders and scientists worldwide consider antibiotic resistance among the world's
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …
Antibiofilm peptides: potential as broad-spectrum agents
D Pletzer, REW Hancock - Journal of bacteriology, 2016 - Am Soc Microbiol
The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic
resistance and relatively few novel compounds or strategies under development or entering …
resistance and relatively few novel compounds or strategies under development or entering …
[HTML][HTML] Synthetic antibiofilm peptides
C De La Fuente-Núñez, MH Cardoso… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Bacteria predominantly exist as multicellular aggregates known as biofilms that are
associated with at least two thirds of all infections and exhibit increased adaptive resistance …
associated with at least two thirds of all infections and exhibit increased adaptive resistance …
Design and assessment of anti-biofilm peptides: steps toward clinical application
M Dostert, CR Belanger, REW Hancock - Journal of innate immunity, 2019 - karger.com
Highly antibiotic resistant, microbial communities, referred to as biofilms, cause various life-
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …
Anti-biofilm peptides as a new weapon in antimicrobial warfare
D Pletzer, SR Coleman, REW Hancock - Current opinion in microbiology, 2016 - Elsevier
Highlights•To date no antibiotics have been specifically developed for biofilm infections.•Anti-
biofilm peptides directly address chronic multi-resistant bacterial infections.•They …
biofilm peptides directly address chronic multi-resistant bacterial infections.•They …
A broad-spectrum antibiofilm peptide enhances antibiotic action against bacterial biofilms
F Reffuveille, C De La Fuente-Nú̃nez… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Biofilm-related infections account for at least 65% of all human infections, but there are no
available antimicrobials that specifically target biofilms. Their elimination by available …
available antimicrobials that specifically target biofilms. Their elimination by available …
Antibiofilm activity of host defence peptides: complexity provides opportunities
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …
[HTML][HTML] Antimicrobial and antibiofilm peptides
A Di Somma, A Moretta, C Canè, A Cirillo, A Duilio - Biomolecules, 2020 - mdpi.com
The increasing onset of multidrug-resistant bacteria has propelled microbiology research
towards antimicrobial peptides as new possible antibiotics from natural sources …
towards antimicrobial peptides as new possible antibiotics from natural sources …
[HTML][HTML] Critical assessment of methods to quantify biofilm growth and evaluate antibiofilm activity of host defence peptides
Biofilms are multicellular communities of bacteria that can adhere to virtually any surface.
Bacterial biofilms are clinically relevant, as they are responsible for up to two-thirds of …
Bacterial biofilms are clinically relevant, as they are responsible for up to two-thirds of …
Host defense (antimicrobial) peptides
E Sun, CR Belanger, EF Haney… - Peptide applications in …, 2018 - Elsevier
Small cationic, amphipathic peptides with critical roles in host defenses often exhibit
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …