Objective Current prevention of peripheral vascular disease (PVD) focuses on blood
pressure control, lipid lowering, and platelet inhibition with statins and aspirin. A critical role …

Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …

Peripheral artery disease is 1 of 3 major clinical manifestations of atherosclerosis, the other
2 being coronary artery and cerebrovascular disease. Despite progress in surgery …

Conclusions This is a dynamic and exciting time in cardiovascular medicine. Recent
advances in understanding of the biologic, cellular, and molecular mechanisms involved in …

Atherosclerosis represents a spectrum of pathologic lesions with diverse clinical sequelae.
In this review, we build upon the paradigm that arteriosclerosis represents an inflammatory …

Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

Cardiovascular disease (CVD) is one of the leading causes of death worldwide. Chronic
atherosclerosis induced vascular inflammation and perturbation of lipid metabolism is …

Atherosclerosis is a lipid-driven disease of the artery characterized by chronic non-resolving
inflammation. Despite availability of excellent lipid-lowering therapies, atherosclerosis …

Inflammation is a critical driver of all stages of atherosclerosis, from lesion development to
plaque rupture. Cytokines are mediators of the immune response and in atherosclerosis, the …

Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …