Inflammation is a complex, multi-scale biologic response to stress that is also required for
repair and regeneration after injury. Despite the repository of detailed data about the cellular …

Inflammation is a complex, multiscale biological response to threats–both internal and
external–to the body, which is also required for proper healing of injured tissue. In turn …

A central goal of industrialized nations is to provide personalized, pre-emptive and
predictive medicine, while maintaining healthcare costs at a minimum. To do so, we must …

Inflammation is a complex, non-linear process central to many of the diseases that affect
both developed and emerging nations. A systems-based understanding of inflammation …

Personalized medicine is a major goal for the future of healthcare, and we suggest that
computational simulations are necessary in order to achieve it. Inflammatory diseases, both …

Trauma, often accompanied by hemorrhage, is a leading cause of death worldwide, often
leading to inflammation-related late complications that include sepsis and multiple organ …

Objectives: To familiarize clinicians with advances in computational disease modeling
applied to trauma and sepsis. Data Sources: PubMed search and review of relevant medical …

Common inflammatome gene signatures as well as disease‐specific signatures were
identified by analyzing 12 expression profiling data sets derived from 9 different tissues …

The pathophysiology of the burn patient manifests the full spectrum of the complexity of the
inflammatory response. In the acute phase, inflammation may have negative effects via …

Effective translational methodologies for knowledge representation are needed in order to
make strides against the constellation of diseases that affect the world today. These …