Retinoblastoma (RB) tumor suppressor proteins are important regulators of the cell cycle
and are implicated in a wide variety of human tumors. Genetic analysis of RB mutations in …

Retinoblastoma proteins are eukaryotic transcriptional corepressors that play central roles in
cell cycle control, among other functions. Although most metazoan genomes encode a …

The retinoblastoma (RB) family transcriptional corepressors regulate diverse cellular events
including cell cycle, senescence, and differentiation. The activity and stability of these …

The identification of the retinoblastoma gene (rb) has sparked intense inves tigation of tumor
suppressor genes. These genes, like oncogenes, can encode transcriptional regulators …

The RB tumor suppressor, a regulator of the cell cycle, apoptosis, senescence, and
differentiation, is frequently mutated in human cancers. We recently described an …

Retinoblastoma tumor suppressor protein (pRb) regulates various biological processes
during development and tumorigenesis. Although the molecular mechanism by which pRb …

Early studies of the retinoblastoma gene (RB) have uncovered its critical role as a regulator
of the G 1/S cell cycle phase progression. Surprisingly, genetic approaches in mammals and …

Since its discovery, the retinoblastoma (RB) tumour-suppressor protein has been a focal
point of cancer research. Accumulating evidence indicates a complex role for RB in cell …

The Retinoblastoma (RB) transcriptional corepressor and related family of pocket proteins
play central roles in cell cycle control and development, and the regulatory networks …

To assess biological roles of the retinoblastoma protein (RB), four independent transgenic
mouse lines expressing human RB with different deletions in the N-terminal region (RBΔN) …