Models for Tumour Cell—Stromal Cell Interactions
JA Eble - The Cancer Handbook, 2005 - Wiley Online Library
Stromal cells in the vicinity of tumour cells are not an inert component of an organ. Cancer
cells induce the fibroblasts of the surrounding connective tissue to develop into carcinoma …
cells induce the fibroblasts of the surrounding connective tissue to develop into carcinoma …
Cancer associated fibroblasts in cancer pathogenesis
OE Franco, AK Shaw, DW Strand… - Seminars in cell & …, 2010 - Elsevier
In the past century, gradual but sustained advances in our understanding of the molecular
mechanisms involved in the growth and invasive properties of cancer cells have led to better …
mechanisms involved in the growth and invasive properties of cancer cells have led to better …
Functional diversity of fibroblasts
HP Rodemann, HO Rennekampff - Tumor-Associated Fibroblasts and their …, 2011 - Springer
Solid tumours are multi-cellular tissues comprised of tumour cells and stromal cells,
including fibroblasts, endothelial cells and inflammatory cells. When a cancer cell …
including fibroblasts, endothelial cells and inflammatory cells. When a cancer cell …
Emerging role of stromal fibroblasts in epithelial cancer
M Rita Rippo, A Procopio… - Current Signal …, 2006 - ingentaconnect.com
The mechanisms involved in the tumor-stroma interaction during carcinoma progression are
an area of intensive investigation. Cancer cells produce a range of growth factors and …
an area of intensive investigation. Cancer cells produce a range of growth factors and …
Tumor–Stroma Interaction and Cancer Progression
The understanding of how normal cells transform into tumor cells and progress to invasive
cancer and metastases continues to evolve. The tumor mass is comprised of a …
cancer and metastases continues to evolve. The tumor mass is comprised of a …
Role of stromal cells in determining tumor and cancer stem cell behaviors and therapeutic response
SJ Reshkin, RA Cardone - Cancers, 2020 - mdpi.com
While research previously focused extensively on the tumor cells, over the last two decades,
the tumor microenvironment (TME) has received increasing attention with a particular …
the tumor microenvironment (TME) has received increasing attention with a particular …
Role of stromal fibroblasts in cancer: promoting or impeding?
F Angeli, G Koumakis, MC Chen, S Kumar… - Tumor Biology, 2009 - karger.com
The basement membrane, immune cells, capillaries, fibroblasts and extracellular matrix
(ECM) constitute the tumour stroma, commonly referred to as the 'reactive stroma'. The …
(ECM) constitute the tumour stroma, commonly referred to as the 'reactive stroma'. The …
Stromal contributions to the carcinogenic process
Tumor‐associated stromal cells are dynamic characters that endorse the carcinogenic
process in a multitude of ways. The tumor microenvironment plays a crucial role throughout …
process in a multitude of ways. The tumor microenvironment plays a crucial role throughout …
Tumor–stromal cell interactions and opportunities for therapeutic intervention
T Udagawa, M Wood - Current opinion in pharmacology, 2010 - Elsevier
Tumor tissue is composed of both cancer cells and stromal cells recruited from normal
tissue. These cells include fibroblastic cells, endothelial cells, and cells of hematopoietic …
tissue. These cells include fibroblastic cells, endothelial cells, and cells of hematopoietic …
Stromal cells can contribute oncogenic signals
TD Tlsty - Seminars in cancer biology, 2001 - Elsevier
The majority of studies of neoplastic transformation have focused attention on events that
occur within transformed cells. These cell autonomous events result in the disruption of …
occur within transformed cells. These cell autonomous events result in the disruption of …