An era of advances in systemic therapies for advanced thyroid cancer

KM Yun, EEW Cohen - JCO Oncology Practice, 2024 - ascopubs.org
Thyroid carcinomas comprise distinct pathologic subtypes. However, advancements in
characterizing the molecular tumorigenesis of thyroid cancers have changed the treatment …

Management of Advanced Thyroid Cancer: Overview, Advances, and Opportunities

S Agosto Salgado, ER Kaye, Z Sargi… - American Society of …, 2023 - ascopubs.org
Thyroid cancer is the most common endocrine malignancy with almost one million people
living with thyroid cancer in the United States. Although early-stage well-differentiated …

Therapeutic options for advanced thyroid cancer

A Jayarangaiah, G Sidhu, J Brown… - … journal of clinical …, 2019 - clinsurggroup.us
Thyroid cancer can be largely classified as well-differentiated, poorly differentiated,
medullary and anaplastic. Differentiated thyroid cancer (DTC) includes follicular and …

Targeted therapy for advanced thyroid cancer: kinase inhibitors and beyond

ME Cabanillas, M Ryder, C Jimenez - Endocrine reviews, 2019 - academic.oup.com
The treatment of advanced thyroid cancer has undergone rapid evolution in the last decade,
with multiple kinase inhibitor drug approvals for each subtype of thyroid cancer and a …

Kinase inhibitors in thyroid cancers

V Sukrithan, P Jain, MH Shah, B Konda - Endocrine Oncology, 2023 - eo.bioscientifica.com
Objective The treatment landscape for thyroid cancers has changed rapidly with the
availability of kinase inhibitors against VEGFR, BRAF, MEK, NTRK, and RET. We provide an …

The treatment of advanced thyroid cancer in the age of novel targeted therapies

R Lirov, FP Worden, MS Cohen - Drugs, 2017 - Springer
Until recently, patients with advanced thyroid cancers had limited options for systemic
treatment. With the introduction of tyrosine kinase inhibitors (TKIs) as a promising new class …

Navigating systemic therapy in advanced thyroid carcinoma: from standard of care to personalized therapy and beyond

SN Rao, ME Cabanillas - Journal of the Endocrine Society, 2018 - academic.oup.com
Thyroid cancer, with the exception of anaplastic thyroid cancer, typically has very favorable
outcomes with the standard therapy. However, those that persist, recur, or metastasize are …

Treatment of advanced thyroid cancer: role of molecularly targeted therapies

LL Covell, AK Ganti - Targeted oncology, 2015 - Springer
Advanced thyroid cancer is not amenable to therapy with conventional cytotoxic
chemotherapy. However, newer advances in the understanding of the molecular …

Clinical Efficacy of Targeted Biologic Agents as Second‐Line Therapy of Advanced Thyroid Cancer

TK Owonikoko, RP Chowdry, Z Chen, S Kim… - The …, 2013 - academic.oup.com
Clinical Efficacy of Targeted Biologic Agents as Second‐Line Therapy of Advanced Thyroid
Cancer | The Oncologist | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

Targeted therapy in thyroid cancer: state of the art

L Valerio, L Pieruzzi, C Giani, L Agate, V Bottici… - Clinical oncology, 2017 - Elsevier
Thyroid cancer typically has a good outcome following standard treatments, which include
surgery, radioactive iodine ablation for differentiated tumours and treatment with thyrotropine …