Background: The role of carbon dioxide (CO2) in the pathogenesis of tumor recurrence after
laparoscopy remains controversial. Using a new rat model, we studied the effect of different …

PURPOSE: Possible mechanisms of movement of malignant cells within the peritoneal
cavity during CO 2 insufflation and laparoscopy involve direct transfer via laparoscopic …

Background: A variety of mechanisms have been proposed to explain tumor growth in port
sites following laparoscopic cancer surgery. We devised two experimental models to …

Background: The application of laparoscopic‐assisted surgery to gastrointestinal
malignancy has lead to the recurrence of malignancy in wounds created during these …

Background: Animal experiments have shown that carbon dioxide (CO 2) laparoscopy
results in more port-site recurrences than gasless laparoscopy. Possible transport of …

Background: Our laboratory has previously shown that tumors are established more easily
and grow larger after laparotomy than after laparoscopy. To characterize these differences in …

Background Experimental and clinical studies, have suggested that the CO 2
pneumoperitoneum influences the development of intraabdominal tumor dissemination and …

Background Conventional laparoscopic surgery uses CO 2 that is dry and cold, which can
damage peritoneal surfaces. It is speculated that disseminated cancer cells may adhere to …

Background The validity of using CO 2 in laparoscopic tumor surgery has not yet been
established. To address this question, we investigated the growth of liver metastases …

Background The oncologic consequences of intraperitoneal carbon dioxide (CO 2)
insufflation during the laparoscopic resection of cancer are under debate. The effect of other …