ABSTRACT DNA methylation reprogramming (DMR) during preimplantation development
erases differentiation-associated, unessential epigenetic information accumulated during …

In mammals, active demethylation of sperm pronuclear DNA shortly after fertilisation is
thought to be important for reprogramming subsequent embryonic development [1–3]. A …

DNA methylation reprogramming (DMR) is believed to be a key process by which
mammalian zygotes gain nuclear totipotency through erasing epigenetic modifications …

Virtually all mammalian species including mouse, rat, pig, cow, and human, but not sheep
and rabbit, undergo genome‐wide epigenetic reprogramming by demethylation of the male …

Early mammalian embryos are thought to gain nuclear totipotency through DNA methylation
reprogramming (DMR). By this process, DNA methylation patterns acquired during …

In mammals, active demethylation of cytosine methylation in the sperm genome prior to
forming a functional zygotic nucleus is thought to be a function of the oocyte cytoplasm …

Epigenetic reprogramming in early preimplantation embryos, that refers to erasing and
remodeling epigenetic marks such as DNA methylation, is essential for differentiation and …

DNA methylation is an important epigenetic modification that undergoes dynamic changes
in mammalian embryogenesis, during which both parental genomes are reprogrammed …

Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …

The reprogramming of DNA methylation in early embryos has been considered to be
essential for the reprogramming of differentiated parental genomes to totipotency, the …