BRAF T1796A Transversion Mutation in Various Thyroid Neoplasms
A high prevalence of activating mutation of the B type Raf kinase (BRAF) gene was recently
reported in papillary thyroid cancer (PTC). However, the frequency of this mutation in several …
reported in papillary thyroid cancer (PTC). However, the frequency of this mutation in several …
Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers
H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
Activating mutations in the BRAF kinase gene have recently been reported in human
cancers. The aim of the present study was to determine the frequency of BRAF mutations in …
cancers. The aim of the present study was to determine the frequency of BRAF mutations in …
BRAF mutations in an Italian cohort of thyroid cancers
L Fugazzola, D Mannavola, V Cirello… - Clinical …, 2004 - Wiley Online Library
Summary objective Recently, a somatic point mutation of the BRAF gene (V599E) has been
identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a …
identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a …
BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications
M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …
received enthusiastic investigation, and significant progress has been made toward …
BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas
MN Nikiforova, ET Kimura, M Gandhi… - The Journal of …, 2003 - academic.oup.com
Activating point mutations of the BRAF gene have been recently reported in papillary thyroid
carcinomas. In this study, we analyzed 320 thyroid tumors and six anaplastic carcinoma cell …
carcinomas. In this study, we analyzed 320 thyroid tumors and six anaplastic carcinoma cell …
[HTML][HTML] BRAF mutation in thyroid cancer
M Xing - Endocrine-related cancer, 2005 - erc.bioscientifica.com
Genetic alteration is the driving force for thyroid tumorigenesis and progression, based upon
which novel approaches to the management of thyroid cancer can be developed. A recent …
which novel approaches to the management of thyroid cancer can be developed. A recent …
BRAFV599E Mutation Is the Leading Genetic Event in Adult Sporadic Papillary Thyroid Carcinomas
E Puxeddu, S Moretti, R Elisei, C Romei… - The Journal of …, 2004 - academic.oup.com
Activating mutations of BRAF have been identified in a variety of human cancers, most
notably melanomas and papillary thyroid carcinomas (PTCs). The aim of the present study …
notably melanomas and papillary thyroid carcinomas (PTCs). The aim of the present study …
Low Frequency of BRAFT1796A Mutations in Childhood Thyroid Carcinomas
A Kumagai, H Namba, VA Saenko… - The Journal of …, 2004 - academic.oup.com
A high prevalence of the activating BRAF mutation, BRAF T1796A, is observed in adult
papillary thyroid carcinomas (PTCs). The prognosis of childhood PTCs is generally fairly …
papillary thyroid carcinomas (PTCs). The prognosis of childhood PTCs is generally fairly …
Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas
MN Nikiforova, R Ciampi, G Salvatore, M Santoro… - Cancer letters, 2004 - Elsevier
Point mutations of the BRAF gene have been recently described with high prevalence in
papillary thyroid carcinomas. However, this molecular alteration has not been studied in …
papillary thyroid carcinomas. However, this molecular alteration has not been studied in …
[PDF][PDF] Mutations of the BRAF gene in papillary thyroid carcinoma in a Korean population
KH Kim, DW Kang, SH Kim, IO Seong… - Yonsei medical …, 2004 - synapse.koreamed.org
The B-type Raf kinase (BRAF) protein is a serine/threonine kinase that has an important role
in cellular proliferation, differentiation, and programmed cell death. The BRAF gene has …
in cellular proliferation, differentiation, and programmed cell death. The BRAF gene has …
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