Endothelial cell–cell junctions maintain a restrictive barrier that is tightly regulated to allow
dynamic responses to permeability-inducing angiogenic factors, as well as to inflammatory …

Vascular endothelial (VE)–cadherin forms homotypic adherens junctions (AJs) in the
endothelium, whereas N-cadherin forms heterotypic adhesion between endothelial cells …

Within blood vessels, endothelial cell–cell and cell–matrix adhesions are crucial to preserve
barrier function, and these adhesions are tightly controlled during vascular development …

ABSTRACT VE-cadherin-based cell-cell junctions form the major restrictive barrier of the
endothelium to plasma proteins and blood cells. The function of VE-cadherin and the actin …

Junction dynamics of endothelial cells are based on the integration of signal transduction,
cytoskeletal remodeling and contraction, which are necessary for the formation and …

The integrity of the endothelium is dependent on cell-cell adhesion, which is mediated by
vascular-endothelial (VE)-cadherin. Proper VE-cadherin-mediated homotypic adhesion is, in …

Cell-cell adhesion in simple epithelia involves the engagement of E-cadherin and nectins,
and the reorganization of the actin cytoskeleton and membrane dynamics by Rho GTPases …

Endothelial cells line the lumen of the vessel wall and are exposed to flow. In linear parts of
the vessel, the endothelial cells experience laminar flow, resulting in endothelial cell …

The role of the RhoGTPase Rac1 in stabilizing mature endothelial adherens junctions (AJs)
is not well understood. In this paper, using a photoactivatable probe to control Rac1 activity …

The formation and stability of epithelial adhesive systems, such as adherens junctions,
desmosomes and tight junctions, rely on a number of cellular processes that ensure a …