Trehalose is a disaccharide consisting of two glucose molecules and is produced by various
organisms, including Escherichia coli via the otsBA operon. It is proposed to be a stress …

OtsA is required for the biosynthesis of trehalose, a nonreducing disaccharide that is
important for bacterial survival and stress responses. In this issue of Chemistry & Biology …

The dissacharide trehalose is an important intracellular osmoprotectant and the OtsA/B
pathway is the principal pathway for trehalose biosynthesis in a wide range of bacterial …

Trehalose accumulates dramatically in microorganisms during heat shock and osmotic
stress and helps protect cells against thermal injury and oxygen radicals. Here we …

The disaccharide trehalose is widely distributed in nature and can serve as a carbon
reservoir, a signaling molecule for controlling glucose metabolism and a stress protectant …

Abstract Trehalose (1-α-d-glucopyranosyl-1-α-d-glucopyranoside), a non-reducing
disaccharide is a major compatible solute, which maintains fluidity of membranes and …

1.5 kb of otsA gene encoding trehalose synthase has been cloned by PCR amplification.
The DNA fragment was ligated to multi-copy vector and transformed to otsBA deleted and …

Trehalose is a nonreducing disaccharide of glucose that functions as a compatible solute in
the stabilization of biological structures under abiotic stress in bacteria, fungi, and …

Trehalose is a chemical chaperone known to protect a variety of organisms against cold
stress. Members of the genus Arthrobacter, which belongs to the Actinomycetales group …

In Escherichia coli, the disaccharide trehalose can be metabolized as a carbon source or be
accumulated as an osmoprotectant under osmotic stress. In hypertonic environments, E. coli …