Systematic review of the efficacy, effectiveness and safety of cell‐based seasonal influenza vaccines for the prevention of laboratory‐confirmed influenza in individuals …

K Jordan, EO Murchu, L Comber… - Reviews in Medical …, 2023 - Wiley Online Library
The most effective means of preventing seasonal influenza is through strain‐specific
vaccination. In this study, we investigated the efficacy, effectiveness and safety of cell‐based …

Immunogenicity and safety of varying dosages of a monovalent 2009 H1N1 influenza vaccine given with and without AS03 adjuvant system in healthy adults and older …

LA Jackson, WH Chen, JT Stapleton… - The Journal of …, 2012 - academic.oup.com
Background. Adjuvanted vaccines have the potential to improve influenza pandemic
response. AS03 adjuvant has been shown to enhance the immune response to inactivated …

Comparative immunogenicity of enhanced seasonal influenza vaccines in older adults: a systematic review and meta-analysis

TWY Ng, BJ Cowling, HZ Gao… - The Journal of …, 2019 - academic.oup.com
Background A number of enhanced influenza vaccines have been developed for use in
older adults, including high-dose, MF59-adjuvanted, and intradermal vaccines. Methods We …

MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection

DT O'Hagan - Expert review of vaccines, 2007 - Taylor & Francis
In preclinical studies, MF59 adjuvant offered improved protection against influenza virus
challenge and significantly reduced the viral load in the lungs of challenged mice. In …

Effectiveness of a MF-59™-adjuvanted pandemic influenza vaccine to prevent 2009 A/H1N1 influenza-related hospitalisation; a matched case-control study

A Steens, EG Wijnans, JP Dieleman… - BMC Infectious …, 2011 - Springer
Background During the 2009 influenza A/H1N1 pandemic, adjuvanted influenza vaccines
were used for the first time on a large scale. Results on the effectiveness of the vaccines in …

The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine

A Podda - Vaccine, 2001 - Elsevier
Elderly people and subjects with underlying chronic diseases are at increased risk for
influenza and related complications. Conventional influenza vaccines provide only limited …

Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for …

E van Doorn, O Pleguezuelos, H Liu… - BMC infectious …, 2017 - Springer
Background Current influenza vaccines, based on antibodies against surface antigens, are
unable to provide protection against newly emerging virus strains which differ from the …

Influenza vaccine effectiveness among high-risk groups: A systematic literature review and meta-analysis of case-control and cohort studies

V Restivo, C Costantino, S Bono… - Human vaccines & …, 2018 - Taylor & Francis
Vaccination represents the most effective intervention to prevent infection, hospitalization
and mortality due to influenza. This meta-analysis quantifies data reporting influenza …

MF59®‐adjuvanted vaccines for seasonal and pandemic influenza prophylaxis

A Banzhoff, M Pellegrini, G Del Giudice… - Influenza and Other …, 2008 - Wiley Online Library
Influenza is a major cause of worldwide morbidity and mortality through frequent seasonal
epidemics and infrequent pandemics. Morbidity and mortality rates from seasonal influenza …

Seasonal influenza vaccination of high-risk adults

P Loubet, P Loulergue, F Galtier… - Expert Review of …, 2016 - Taylor & Francis
Introduction: Adults at a high risk of severe influenza, because of their age and/or underlying
health disorders, should receive seasonal influenza vaccination in order to reduce the …