The aim of the present study was to prepare, characterize, and evaluate solid lipid
nanoparticles (SLNs) containing docetaxel (DTX) to improve the efficacy of this …

The purpose of the study was to design lipid-based-nanosuspensions (LNS) for Docetaxel
(DTX) without Tween 80 for clinical intravenous administration (iv). DTX-LNS were prepared …

Over the past few years, taxanes have emerged as a new class of anticancer drugs.
Docetaxel (DTX) the prototype of this class has been approved for the treatment of broad …

Background Metastasis causes the most breast cancer-related deaths in women. Here, we
investigated the antitumor effect of solid lipid nanoparticles (SLN-DTX) when used in the …

The aim of this study was to develop docetaxel-incorporated lipid nanoparticles (DTX-NPs)
to improve the pharmacokinetic behaviour of docetaxel (DTX) after oral and parenteral …

Human hepatocellular carcinoma (HCC) is one of the major causes of death worldwide.
Targeted uptake of therapeutic agent in the cell-, tissue-or disease-specific manner …

Docetaxel (DCX) is a second generation taxane. It is approved by the US Food and Drug
Administration for the treatment of various types of cancer, including breast, non-small cell …

Due to its excellent biocompatibility, biodegradability, and its ability to modify the
physicochemical properties of nanoparticles, chitosan has been widely used as a coating …

Docetaxel is a potent anticancer drug, but development of an oral formulation has been
hindered mainly due to its poor oral bioavailability. In this study, solid lipid nanoparticles …

Docetaxel was used extensively in ovarian cancer treatment in the combination with
platinum compound. However, the serious side effect of clinically available formulation limits …