In cystic fibrosis inhalation of drugs for the treatment of CF related lung disease has been
proven to be highly effective. Consequently, an increasing number of drugs and devices …

Key points There have been significant advances in both inhalation medicines and delivery
devices with “intelligent nebulisers” and “dry-powder inhalers” becoming commonplace in …

Cystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians
associated with early death. Although the faulty gene is expressed in epithelia throughout …

Cystic fibrosis (CF) patients use several therapies to treat chronic inflammation and infection
in the lungs and to improve airway clearance. Inhaled therapies in CF typically include …

Background Nebuliser systems are used to deliver medications to control the symptoms and
the progression of lung disease in people with cystic fibrosis. Many types of nebuliser …

Background Recurrent wheeze and breathlessness are common in people with cystic
fibrosis, and bronchodilators are commonly prescribed. Despite their wide‐scale and often …

Rationale: Cystic fibrosis (CF) is an autosomal recessive disease characterized by abnormal
airways secretions, chronic endobronchial infection, and progressive airway obstruction …

Chronic airways infection and inflammation is the greatest source of morbidity and mortality
in cystic fibrosis (CF) patients. Many organisms can be found in the lower respiratory tract of …

Several inhaled drugs for use by cystic fibrosis (CF) patients are formulated for nebulizer use
only. This therapy is time consuming and includes the risk of contamination of the …

Rationale: Cystic fibrosis is a recessive genetic disease characterized by dehydration of the
airway surface liquid and impaired mucociliary clearance. As a result, individuals with the …