Expansion in CD39+ CD4+ Immunoregulatory T Cells and Rarity of Th17 Cells in HTLV-1 Infected Patients Is Associated with Neurological Complications
FE Leal, LC Ndhlovu, AM Hasenkrug… - PLoS neglected …, 2013 - journals.plos.org
HTLV-1 infection is associated with several inflammatory disorders, including the
neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis …
neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis …
CD80+ and CD86+B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis
SM Menezes, D Decanine, D Brassat, R Khouri… - Journal of …, 2014 - Springer
Background Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the
incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic …
incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic …
The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in …
J Michaëlsson, HMR Barbosa, KA Jordan… - BMC immunology, 2008 - Springer
Background CD4+ CD25 high regulatory T (T Reg) cells modulate antigen-specific T cell
responses, and can suppress anti-viral immunity. In HTLV-1 infection, a selective decrease …
responses, and can suppress anti-viral immunity. In HTLV-1 infection, a selective decrease …
CD49d is upregulated in circulating T lymphocytes from HTLV-1-infected patients
LT Janahú, CA Da Costa, ACR Vallinoto… - …, 2021 - karger.com
Abstract Introduction: HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a chronic progressive myelopathy associated with an inflammation of the …
(HAM/TSP) is a chronic progressive myelopathy associated with an inflammation of the …
HTLV-1 induces a Th1-like state in CD4+ CCR4+ T cells that produces an inflammatory positive feedback loop via astrocytes in HAM/TSP
Y Yamano, A Coler-Reilly - Journal of neuroimmunology, 2017 - Elsevier
The main feature of Human T-lymphotropic virus type I (HTLV-1)-associated
myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis is a virus-induced …
myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis is a virus-induced …
Abnormally High Levels of Virus-Infected IFN-γ+CCR4+CD4+CD25+ T Cells in a Retrovirus-Associated Neuroinflammatory Disorder
Y Yamano, N Araya, T Sato, A Utsunomiya, K Azakami… - PloS one, 2009 - journals.plos.org
Background Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus associated
with both HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), which is a …
with both HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), which is a …
Th17/IL-17 Axis in HTLV-1-associated myelopathy tropical spastic Paraparesis and multiple sclerosis: novel insights into the immunity during HAMTSP
M Shafiei, SH Mozhgani - Molecular Neurobiology, 2023 - Springer
Human T lymphotropic virus–associated myelopathy/tropical spastic paraparesis
(HTLV/TSP), also known as HTLV-associated myelopathy/tropical spastic paraparesis …
(HTLV/TSP), also known as HTLV-associated myelopathy/tropical spastic paraparesis …
HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T cells …
ES Gudo, SD Silva-Barbosa, L Linhares-Lacerda… - Virology Journal, 2015 - Springer
Background The mechanisms through which HTLV-1 leads to and maintains damage in the
central nervous system of patients undergoing HTLV-1 associated myelopathy/tropical …
central nervous system of patients undergoing HTLV-1 associated myelopathy/tropical …
How does interleukin 15 contribute to the pathogenesis of HTLV type 1-associated myelopathy/tropical spastic paraparesis?
N Azimi, J Mariner, S Jacobson… - AIDS research and …, 2000 - liebertpub.com
HTLV-1 is the etiological agent of a neurological disease named HAM/TSP that has clinical
characteristics similar to those of multiple sclerosis (MS). The PBMC obtained from …
characteristics similar to those of multiple sclerosis (MS). The PBMC obtained from …
Retrovirally induced CTL degranulation mediated by IL-15 expression and infection of mononuclear phagocytes in patients with HTLV-I–associated neurologic …
Y Enose-Akahata, U Oh, C Grant… - Blood, The Journal of …, 2008 - ashpublications.org
CD8+ T cells contribute to central nervous system inflammation in human T-cell
lymphotropic virus type I (HTLV-I)–associated myelopathy/tropical spastic paraparesis …
lymphotropic virus type I (HTLV-I)–associated myelopathy/tropical spastic paraparesis …